{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSM878095": {"SAMPLE ID": "donor 1 (MSC population #276)", "GENDER": "female", "AGE": "42 yrs (middle-aged)", "PASSAGE": "passage 1"}}, {"GSM878096": {"SAMPLE ID": "donor 2 (MSC population #353)", "GENDER": "female", "AGE": "67 yrs (middle-aged)", "PASSAGE": "passage 2"}}, {"GSM878097": {"SAMPLE ID": "donor 3 (MSC population #295)", "GENDER": "male", "AGE": "61 yrs (middle-aged)", "PASSAGE": "passage 1"}}, {"GSM878098": {"SAMPLE ID": "donor 4 (MSC population #296)", "GENDER": "female", "AGE": "62 yrs (middle-aged)", "PASSAGE": "passage 1"}}, {"GSM878099": {"SAMPLE ID": "donor 5 (MSC population #247)", "GENDER": "female", "AGE": "56 yrs (middle-aged)", "PASSAGE": "passage 1"}}, {"GSM878104": {"SAMPLE ID": "donor 1 with primary osteoporosis (MSC population #535)", "GENDER": "female", "AGE": "79 yrs (elderly)", "PASSAGE": "passage 1"}}, {"GSM878105": {"SAMPLE ID": "donor 2 with primary osteoporosis (MSC population #547)", "GENDER": "female", "AGE": "94 yrs (elderly)", "PASSAGE": "passage 1"}}, {"GSM878106": {"SAMPLE ID": "donor 3 with primary osteoporosis (MSC population #558)", "GENDER": "female", "AGE": "87 yrs (elderly)", "PASSAGE": "passage 2"}}, {"GSM878107": {"SAMPLE ID": "donor 4 with primary osteoporosis (MSC population #572)", "GENDER": "female", "AGE": "82 yrs (elderly)", "PASSAGE": "passage 1"}}, {"GSM878108": {"SAMPLE ID": "donor 5 with primary osteoporosis (MSC population #573)", "GENDER": "female", "AGE": "89 yrs (elderly)", "PASSAGE": "passage 1"}}], "id": 4424, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "In the present study we analyzed the effect of primary osteoporosis and advanced donor age on the transcriptome of human mesenchymal stem...", "geo_gse_id": "E-GEOD-35956", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 4, "sample_count": 10, "tags": ["bone", "bone marrow", "hip", "middle", "neck", "osteoarthritis", "osteoporosis"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "effects-of-primary-osteoporosis-and-advanced-age-o", "geo_id_plat": "E-GEOD-35956_A-AFFY-44", "name": "Effects of Primary Osteoporosis and Advanced Age on Human Mesenchymal Stem Cells", "created": "Sep.19, 2014", "summary": "In the present study we analyzed the effect of primary osteoporosis and advanced donor age on the transcriptome of human mesenchymal stem cells (hMSC; alternatively named mesenchymal stromal cells) from bone marrow. Human MSC of elderly patients suffering from osteoporosis were isolated from femoral heads after low-energy fracture of the femoral neck. Control cells were obtained from bone marrow of femoral heads of middle-aged, non-osteoporotic donors after total hip arthroplasty. Cells were isolated from human bone marrow according to the previously described protocol (Noth et al., 2002, J Orthop Res, 20/5, 1060-1069) under agreement of the local Ethics Committee of the University of W\u00fcrzburg. Human MSC of elderly patients suffering from osteoporosis were isolated from femoral heads after low-energy fracture of the femoral neck. Additional criteria for confirming primary osteoporosis in these donors were vertebrae fractures and advanced age. Bone marrow of middle-aged, non-osteoporotic donors was obtained of femoral heads after total hip arthroplasty due to osteoarthritis and/or hip dysplasia. RNA samples were taken from passage 1 or passage 2.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-35956", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-35956/samples/"}