Dataset: Host response and dysfunction in the CNS during chronic simian immunodeficiency virus infection [human study]
Finding the differences in gene expression in three regions of the brai, basal ganglia, white matter, and frontal cortex, in normal, HIV...
Finding the differences in gene expression in three regions of the brai, basal ganglia, white matter, and frontal cortex, in normal, HIV infected, HIV inefected with neurocognitive impairment, and HIV infected with both neurocognitive impairment and encephalitis patients. We used microarrays to identify differentially expressed genes in normal, HIV infected, HIV inefected with neurocognitive impairment, and HIV infected with both neurocognitive impairment and encephalitis patients. Samples from three different brain regions from normal, HIV infected, HIV infected with neurocognitive impairment (HAD: HIV-associated dementia), and HIV infected with both neurocognitive impairment and encephalitis (HIVE: HIV encephalitis) patients were collected for RNA isolation and supsequent Affymetrix microarray analysis. We sought to obtain gene expression levels in different brain regions to find implication of HIV and the neurological impairment and inflammation associated with HIV infection.
- Species:
- human
- Samples:
- 72
- Source:
- E-GEOD-35864
- Updated:
- Dec.12, 2014
- Registered:
- Sep.19, 2014
Factors:
(via ArrayExpress)
| Sample | AGE | RACE | PHENOTYPE | ORGANISM PART | SEX |
|---|---|---|---|---|---|
| GSM876838 | 44 | White | normal (control) | White matter | male |
| GSM876839 | 53 | White | normal (control) | White matter | male |
| GSM876840 | 63 | Hispanic | normal (control) | White matter | male |
| GSM87684 | 58 | White | normal (control) | White matter | male |
| GSM876842 | 34 | White | normal (control) | White matter | male |
| GSM876843 | 48 | White | normal (control) | White matter | female |
| GSM876844 | 49 | White | HIV Infected | White matter | male |
| GSM876845 | 47 | White | HIV Infected | White matter | male |
| GSM876846 | 44 | White | HIV Infected | White matter | male |
| GSM876847 | 59 | White | HIV Infected | White matter | male |
| GSM876848 | 60 | White | HIV Infected | White matter | male |
| GSM876849 | 39 | White | HIV Infected | White matter | male |
| GSM876850 | 33 | Black | HIV Infected with neurocognitive impairment (HAD: HIV-associated dementia) | White matter | male |
| GSM87685 | 35 | White | HIV Infected with neurocognitive impairment (HAD: HIV-associated dementia) | White matter | male |
| GSM876852 | 57 | White | HIV Infected with neurocognitive impairment (HAD: HIV-associated dementia) | White matter | male |
| GSM876853 | 36 | Hispanic | HIV Infected with neurocognitive impairment (HAD: HIV-associated dementia) | White matter | male |
| GSM876854 | 52 | White | HIV Infected with neurocognitive impairment (HAD: HIV-associated dementia) | White matter | male |
| GSM876855 | 41 | Hispanic | HIV Infected with neurocognitive impairment (HAD: HIV-associated dementia) | White matter | male |
| GSM876854 | 52 | White | HIV Infected with neurocognitive impairment (HAD: HIV-associated dementia) | White matter | male |
| GSM876857 | 48 | White | HIV Infected with HAD and HIV encephalitis (HIVE) | White matter | male |
| GSM876858 | 32 | White | HIV Infected with HAD and HIV encephalitis (HIVE) | White matter | male |
| GSM876859 | 39 | White | HIV Infected with HAD and HIV encephalitis (HIVE) | White matter | male |
| GSM876860 | 55 | White | HIV Infected with HAD and HIV encephalitis (HIVE) | White matter | male |
| GSM87686 | 41 | Hispanic | HIV Infected with HAD and HIV encephalitis (HIVE) | White matter | male |
| GSM876862 | 44 | White | normal (control) | Frontal cortex | male |
| GSM876863 | 53 | White | normal (control) | Frontal cortex | male |
| GSM876864 | 63 | Hispanic | normal (control) | Frontal cortex | male |
| GSM876865 | 58 | White | normal (control) | Frontal cortex | male |
| GSM876866 | 34 | White | normal (control) | Frontal cortex | male |
| GSM876867 | 48 | White | normal (control) | Frontal cortex | female |
| GSM876868 | 49 | White | HIV Infected | Frontal cortex | male |
| GSM876869 | 47 | White | HIV Infected | Frontal cortex | male |
| GSM876870 | 44 | White | HIV Infected | Frontal cortex | male |
| GSM87687 | 59 | White | HIV Infected | Frontal cortex | male |
| GSM876872 | 60 | White | HIV Infected | Frontal cortex | male |
| GSM876873 | 39 | White | HIV Infected | Frontal cortex | male |
| GSM876874 | 33 | Black | HIV Infected with neurocognitive impairment (HAD: HIV-associated dementia) | Frontal cortex | male |
| GSM876875 | 35 | White | HIV Infected with neurocognitive impairment (HAD: HIV-associated dementia) | Frontal cortex | male |
| GSM876876 | 57 | White | HIV Infected with neurocognitive impairment (HAD: HIV-associated dementia) | Frontal cortex | male |
| GSM876877 | 36 | Hispanic | HIV Infected with neurocognitive impairment (HAD: HIV-associated dementia) | Frontal cortex | male |
| GSM876878 | 52 | White | HIV Infected with neurocognitive impairment (HAD: HIV-associated dementia) | Frontal cortex | male |
| GSM876879 | 41 | Hispanic | HIV Infected with neurocognitive impairment (HAD: HIV-associated dementia) | Frontal cortex | male |
| GSM876878 | 52 | White | HIV Infected with neurocognitive impairment (HAD: HIV-associated dementia) | Frontal cortex | male |
| GSM87688 | 48 | White | HIV Infected with HAD and HIV encephalitis (HIVE) | Frontal cortex | male |
| GSM876882 | 32 | White | HIV Infected with HAD and HIV encephalitis (HIVE) | Frontal cortex | male |
| GSM876883 | 39 | White | HIV Infected with HAD and HIV encephalitis (HIVE) | Frontal cortex | male |
| GSM876884 | 55 | White | HIV Infected with HAD and HIV encephalitis (HIVE) | Frontal cortex | male |
| GSM876885 | 41 | Hispanic | HIV Infected with HAD and HIV encephalitis (HIVE) | Frontal cortex | male |
| GSM876886 | 44 | White | normal (control) | Basal ganglia | male |
| GSM876887 | 53 | White | normal (control) | Basal ganglia | male |
| GSM876888 | 63 | Hispanic | normal (control) | Basal ganglia | male |
| GSM876889 | 58 | White | normal (control) | Basal ganglia | male |
| GSM876890 | 34 | White | normal (control) | Basal ganglia | male |
| GSM87689 | 48 | White | normal (control) | Basal ganglia | female |
| GSM876892 | 49 | White | HIV Infected | Basal ganglia | male |
| GSM876893 | 47 | White | HIV Infected | Basal ganglia | male |
| GSM876894 | 44 | White | HIV Infected | Basal ganglia | male |
| GSM876895 | 59 | White | HIV Infected | Basal ganglia | male |
| GSM876896 | 60 | White | HIV Infected | Basal ganglia | male |
| GSM876897 | 39 | White | HIV Infected | Basal ganglia | male |
| GSM876898 | 33 | Black | HIV Infected with HAD | Basal ganglia | male |
| GSM876899 | 35 | White | HIV Infected with HAD | Basal ganglia | male |
| GSM876900 | 57 | White | HIV Infected with HAD | Basal ganglia | male |
| GSM87690 | 36 | Hispanic | HIV Infected with HAD | Basal ganglia | male |
| GSM876902 | 52 | White | HIV Infected with HAD | Basal ganglia | male |
| GSM876903 | 41 | Hispanic | HIV Infected with HAD | Basal ganglia | male |
| GSM876902 | 52 | White | HIV Infected with HAD | Basal ganglia | male |
| GSM876905 | 48 | White | HIV Infected with HAD and encephalitis | Basal ganglia | male |
| GSM876906 | 32 | White | HIV Infected with HAD and encephalitis | Basal ganglia | male |
| GSM876907 | 39 | White | HIV Infected with HAD and encephalitis | Basal ganglia | male |
| GSM876908 | 55 | White | HIV Infected with HAD and encephalitis | Basal ganglia | male |
| GSM876909 | 41 | Hispanic | HIV Infected with HAD and encephalitis | Basal ganglia | male |