ArrayExpress Uploader0mousecontrolGGPP knockout6778arrayexpress_sid6GGPPS was the key enzyme of mevalonate metabolic pathway which was used to synthesize the geranylgeranyl pyrophosphate (GGPP). When we...E-GEOD-35755/profile/8773/arrayexpressuploader12cellsertoli cellDec.12, 2014FalseE-GEOD-35755_A-AFFY-45gene-expression-profile-after-ggpps-deletion-in-segene expression profile after GGPPS deletion in sertoli cellNov.12, 2014GGPPS was the key enzyme of mevalonate metabolic pathway which was used to synthesize the geranylgeranyl pyrophosphate (GGPP). When we deletion the GGPPS in the sertoli cell and the germ cell loss were found . We used microarrays to detail the global programme of gene expression after GGPPS deletion in sertoli cell and identified 1623 gene expression level change more than 2 times. Primary sertoli cells from 3 days old of control and KO mice for RNA extraction and hybridization on Affymetrix microarrays, every group primare sertoli cell were from more than 30 mice.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-35755http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-35755/samples/