ArrayExpress Uploader0mouse10-week-oldtestismale10-week-oldovaryfemale1-day oldtestismale1-day oldovaryfemale15.5 days postcoitumtestismale15.5 days postcoitumovaryfemale6776arrayexpress_sid6Prophase I of meiosis involves dynamic chromosome segregation processes including synapsis, meiotic recombination, and cohesion. Genetic...22648182E-GEOD-35734/profile/8773/arrayexpressuploader36chromosomeinfertilityDec.12, 2014FalseE-GEOD-35734_A-AFFY-45screening-of-genes-involved-in-chromosome-segregatScreening of genes involved in chromosome segregation in meiosis INov.12, 2014Prophase I of meiosis involves dynamic chromosome segregation processes including synapsis, meiotic recombination, and cohesion. Genetic defects in genes participating in these processes consistently cause reproduction failure in mice. To identify candidate genes responsible for infertility or recurrent pregnancy loss in humans, we performed expression profiling of male and female gonads of mice undergoing meiotic prophase I. Both male and female gonads at 15.5 days postcoitum, neonatal day 1 and 10 weeks postpartum were dissected from mice for RNA extraction and subjected to hybridization on Affymetrix microarrays.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-35734http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-35734/samples/