Dataset: Human s.c adipose tissue gene expression during diet-induced weight loss

Obesity has considerable effects on morbidity and mortality and the prevalence of obesity has been increasing rapidly worldwide during...

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Obesity has considerable effects on morbidity and mortality and the prevalence of obesity has been increasing rapidly worldwide during the past two decades. Even if obesity affects the entire individual, adipose tissue play a central role in the development of obesity. Expression profiling of adipose tissue may give insights into mechanisms contributing to obesity and obesity-related disorders. 24 obese subjects (6 women and 18 men, BMI 37.6 ± 4.9) received a very low calorie diet (450 kcal/d, Cambridge diet or Modifast) for 16 weeks. On average, patients lost 27.7 kg during the diet. Microarray expression analysis (Affymetrix U133A) in subcutaneous adipose tissue was performed before diet and after 16 weeks of diet.

Species:: human
Samples:: 48
Source:: E-GEOD-35710
PubMed:: 23264395
Updated:: Dec.12, 2014
Registered:: Jun.18, 2014

Factors: (via ArrayExpress)

Sample	PATIENT	ORGANISM PART	DIET
GSM873747	female 6	female	After diet
GSM873746	female 6	female	Before diet
GSM873745	male 18	male	After diet
GSM873744	male 18	male	Before diet
GSM873743	male 17	male	After diet
GSM873742	male 17	male	Before diet
GSM87374	male 16	male	After diet
GSM873740	male 16	male	Before diet
GSM873739	male 15	male	After diet
GSM873738	male 15	male	Before diet
GSM873737	male 14	male	After diet
GSM873736	male 14	male	Before diet
GSM873735	male 13	male	After diet
GSM873734	male 13	male	Before diet
GSM873733	male 12	male	After diet
GSM873732	male 12	male	Before diet
GSM87373	male 11	male	After diet
GSM873730	male 11	male	Before diet
GSM873729	male 10	male	After diet
GSM873728	male 10	male	Before diet
GSM873727	male 9	male	After diet
GSM873726	male 9	male	Before diet
GSM873725	male 8	male	After diet
GSM873724	male 8	male	Before diet
GSM873723	male 7	male	After diet
GSM873722	male 7	male	Before diet
GSM87372	male 6	male	After diet
GSM873720	male 6	male	Before diet
GSM873719	male 5	male	After diet
GSM873718	male 5	male	Before diet
GSM873717	female 5	female	After diet
GSM873716	female 5	female	Before diet
GSM873715	male 4	male	After diet
GSM873714	male 4	male	Before diet
GSM873713	male 3	male	After diet
GSM873712	male 3	male	Before diet
GSM8737	male 2	male	After diet
GSM873710	male 2	male	Before diet
GSM873709	male 1	male	After diet
GSM873708	male 1	male	Before diet
GSM873707	female 4	female	After diet
GSM873706	female 4	female	Before diet
GSM873705	female 3	female	After diet
GSM873704	female 3	female	Before diet
GSM873703	female 2	female	After diet
GSM873702	female 2	female	Before diet
GSM87370	female 1	female	After diet
GSM873700	female 1	female	Before diet