Dataset: Human s.c adipose tissue gene expression during diet-induced weight loss

Obesity has considerable effects on morbidity and mortality and the prevalence of obesity has been increasing rapidly worldwide during...

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Obesity has considerable effects on morbidity and mortality and the prevalence of obesity has been increasing rapidly worldwide during the past two decades. Even if obesity affects the entire individual, adipose tissue play a central role in the development of obesity. Expression profiling of adipose tissue may give insights into mechanisms contributing to obesity and obesity-related disorders. 24 obese subjects (6 women and 18 men, BMI 37.6 ± 4.9) received a very low calorie diet (450 kcal/d, Cambridge diet or Modifast) for 16 weeks. On average, patients lost 27.7 kg during the diet. Microarray expression analysis (Affymetrix U133A) in subcutaneous adipose tissue was performed before diet and after 16 weeks of diet.

Species:: human
Samples:: 48
Source:: E-GEOD-35710
PubMed:: 23264395
Updated:: Dec.12, 2014
Registered:: Jun.18, 2014

Factors: (via ArrayExpress)

Sample	PATIENT	DIET	ORGANISM PART
GSM873747	female 6	After diet	female
GSM873746	female 6	Before diet	female
GSM873745	male 18	After diet	male
GSM873744	male 18	Before diet	male
GSM873743	male 17	After diet	male
GSM873742	male 17	Before diet	male
GSM87374	male 16	After diet	male
GSM873740	male 16	Before diet	male
GSM873739	male 15	After diet	male
GSM873738	male 15	Before diet	male
GSM873737	male 14	After diet	male
GSM873736	male 14	Before diet	male
GSM873735	male 13	After diet	male
GSM873734	male 13	Before diet	male
GSM873733	male 12	After diet	male
GSM873732	male 12	Before diet	male
GSM87373	male 11	After diet	male
GSM873730	male 11	Before diet	male
GSM873729	male 10	After diet	male
GSM873728	male 10	Before diet	male
GSM873727	male 9	After diet	male
GSM873726	male 9	Before diet	male
GSM873725	male 8	After diet	male
GSM873724	male 8	Before diet	male
GSM873723	male 7	After diet	male
GSM873722	male 7	Before diet	male
GSM87372	male 6	After diet	male
GSM873720	male 6	Before diet	male
GSM873719	male 5	After diet	male
GSM873718	male 5	Before diet	male
GSM873717	female 5	After diet	female
GSM873716	female 5	Before diet	female
GSM873715	male 4	After diet	male
GSM873714	male 4	Before diet	male
GSM873713	male 3	After diet	male
GSM873712	male 3	Before diet	male
GSM8737	male 2	After diet	male
GSM873710	male 2	Before diet	male
GSM873709	male 1	After diet	male
GSM873708	male 1	Before diet	male
GSM873707	female 4	After diet	female
GSM873706	female 4	Before diet	female
GSM873705	female 3	After diet	female
GSM873704	female 3	Before diet	female
GSM873703	female 2	After diet	female
GSM873702	female 2	Before diet	female
GSM87370	female 1	After diet	female
GSM873700	female 1	Before diet	female