ArrayExpress Uploader0mouse1 dayMCAO-induced stroke1 dayMCAO-induced stroke1 daysham surgery1 dayMCAO-induced stroke1 daysham surgery1 dayMCAO-induced stroke1 daysham surgery1 dayMCAO-induced stroke1 daysham surgery1 dayLPS-induced neuroinflammation1 dayLPS-induced neuroinflammation1 dayLPS-induced neuroinflammation1 dayLPS-induced neuroinflammation1 dayLPS-induced neuroinflammation1 daysaline injection1 daysaline injection1 daysaline injection1 daysaline injection3 daysMCAO-induced stroke3 daysMCAO-induced stroke3 daysMCAO-induced stroke7 daysMCAO-induced stroke7 daysMCAO-induced stroke7 daysMCAO-induced stroke3 dayssham surgery3 dayssham surgery3 dayssham surgery7 dayssham surgery7 dayssham surgery7 dayssham surgery6763arrayexpress_sid6Reactive astrogliosis is characterized by a profound change in astrocyte phenotype in response to all CNS injuries and diseases. To...E-GEOD-35338/profile/8773/arrayexpressuploader230arteryastrocytecerebral artery occlusionlipopolysaccharidemiddlemiddle cerebral arterystrokeDec.12, 2014Falseexpression-data-from-reactive-astrocytes-acutely-pE-GEOD-35338_A-AFFY-45Expression data from reactive astrocytes acutely purified from young adult mouse brainsNov.12, 2014Reactive astrogliosis is characterized by a profound change in astrocyte phenotype in response to all CNS injuries and diseases. To better understand the reactive astrocyte state, we used Affymetrix GeneChip arrays to profile gene expression in populations of reactive astrocytes isolated at various time points after induction using two different mouse injury models, ischemic stroke and neuroinflammation. Young adult male mice underwent middle cerebral artery occlusion (MCAO) to produce ischemic stroke or control sham surgery. Young adult mice were injected intraperitoneally with 5 mg/kg lipopolysaccharide (LPS) to produce neuroinflammation or saline for control. Astrocytes were acutely purified from control and injured brains at 1 day after injury for LPS/saline injection and 1, 3 days and 7 days after MCAO/sham surgeries.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-35338http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-35338/samples/