ArrayExpress Uploader0mouseWTWTWTAlb/AEG-1 TransgenicAlb/AEG-1 TransgenicAlb/AEG-1 Transgenic8595arrayexpress_sid8Astrocyte elevated gene-1 (AEG-1) as a positive inducer of hepatocellular carcinoma (HCC). Transgenic mice with hepatocyte-specific...E-GEOD-34669/profile/8773/arrayexpressuploader16astrocytecarcinomahepatocellular carcinomahepatocyteliverDec.12, 2014Falseastrocyte-elevated-gene-1-aeg-1-promotes-hepatocarE-GEOD-34669_A-AFFY-36Astrocyte elevated gene-1 (AEG-1) promotes hepatocarcinogenesis: novel insights from a mouse modelNov.24, 2014Astrocyte elevated gene-1 (AEG-1) as a positive inducer of hepatocellular carcinoma (HCC). Transgenic mice with hepatocyte-specific expression of AEG-1 were challenged with N-nitrosodiethylamine (DEN) and developed multinodular HCC with steatotic features. Thus, we have identified the follwoing AEG-1 functions: induction of steatosis, inhibition of senescence and activation of coagulation pathway to augment an aggressive hepatocarcinogenic phenotype. Transgenic Mice liver tumors compared against WT mice liver tumors.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-34669http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-34669/samples/