{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSM85173": {"CELL LINE": "Mino"}}, {"GSM85173": {"CELL LINE": "Mino"}}, {"GSM85173": {"CELL LINE": "Mino"}}, {"GSM85173": {"CELL LINE": "Mino"}}, {"GSM851735": {"CELL LINE": "Rec-1"}}, {"GSM851735": {"CELL LINE": "Rec-1"}}, {"GSM851735": {"CELL LINE": "Rec-1"}}, {"GSM851735": {"CELL LINE": "Rec-1"}}, {"GSM851739": {"CELL LINE": "SP-49"}}, {"GSM851739": {"CELL LINE": "SP-49"}}, {"GSM851739": {"CELL LINE": "SP-49"}}, {"GSM851739": {"CELL LINE": "SP-49"}}], "id": 4351, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "We identified recurrent NOTCH1 mutations in 12% of MCLs. 2 out of 10 tested MCL cell lines (Rec-1 and SP-49) were sensitive to inhibition...", "geo_gse_id": "E-GEOD-34602", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 12, "tags": ["cell", "notch"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_id_plat": "E-GEOD-34602_A-AFFY-44", "slug": "expression-data-from-3-gamma-secretase-or-mock-tre", "geo_gds_id": "", "name": "Expression data from 3 gamma-secretase or mock-treated mantle cell lymphoma (MCL) cell lines", "created": "Sep.17, 2014", "summary": "We identified recurrent NOTCH1 mutations in 12% of MCLs. 2 out of 10 tested MCL cell lines (Rec-1 and SP-49) were sensitive to inhibition of the NOTCH pathway by gamma-secretase inhibition. The aim of this study was to identify transcriptional targets of NOTCH signaling in MCL. 3 MCL cell lines (Mino, Rec-1, SP-49 treated with Mock or 1 micromolar compound E for 24 hours, in duplicate.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-34602", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-34602/samples/"}