ArrayExpress Uploader0humanMinoMinoMinoMinoRec-1Rec-1Rec-1Rec-1SP-49SP-49SP-49SP-494351arrayexpress_sid4We identified recurrent NOTCH1 mutations in 12% of MCLs. 2 out of 10 tested MCL cell lines (Rec-1 and SP-49) were sensitive to inhibition...E-GEOD-34602/profile/8773/arrayexpressuploader112cellnotchDec.12, 2014FalseE-GEOD-34602_A-AFFY-44expression-data-from-3-gamma-secretase-or-mock-treExpression data from 3 gamma-secretase or mock-treated mantle cell lymphoma (MCL) cell linesSep.17, 2014We identified recurrent NOTCH1 mutations in 12% of MCLs. 2 out of 10 tested MCL cell lines (Rec-1 and SP-49) were sensitive to inhibition of the NOTCH pathway by gamma-secretase inhibition. The aim of this study was to identify transcriptional targets of NOTCH signaling in MCL. 3 MCL cell lines (Mino, Rec-1, SP-49 treated with Mock or 1 micromolar compound E for 24 hours, in duplicate.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-34602http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-34602/samples/