ArrayExpress Uploaderarrayexpress_sidmouse500 mg/l losartan500 mg/l losartan500 mg/l losartan500 mg/l losartan500 mg/l losartan50 mg/kg aliskiren50 mg/kg aliskiren50 mg/kg aliskiren50 mg/kg aliskiren50 mg/kg aliskiren672206The role of the renin-angiotensin system in chronic kidney disease involves multiple peptides and receptors. Exerting antipodal...22791343E-GEOD-34552/profile/8773/arrayexpressuploader110diseasekidneykidney diseaserenin-angiotensin systemDec.12, 2014Falseexpression-data-from-mouse-kidney-tissueE-GEOD-34552_A-AFFY-45Expression data from mouse kidney tissueNov.12, 2014The role of the renin-angiotensin system in chronic kidney disease involves multiple peptides and receptors. Exerting antipodal pathophysiological mechanisms, renin inhibition and AT1 antagonism ameliorate renal damage. This is a comparison between the renin inhibitor aliskiren with the At1 antagonist losartan in mice with chronic kidney disease due to renal ablation. Renal tissue from ablated mice was used after 6-week treatment with either 500 mg/l losartan or 50 mg/kg aliskiren per day (n = 5)http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-34552http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-34552/samples/