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<biogps><data><item key="owner">ArrayExpress Uploader</item><item key="pop_total">0</item><item key="species">mouse</item><item key="factors"><item><item key="GSM850394"><item key="GENOTYPE">U19/Eaf2 +/+</item></item></item><item><item key="GSM850395"><item key="GENOTYPE">U19/Eaf2 -/-</item></item></item></item><item key="id">6720</item><item key="ownerprofile_id">arrayexpress_sid</item><item key="platform">6</item><item key="summary_wrapped">To elucidate potential mechanisms of U19/EAF2 action, we performed cDNA microarray analysis and identified 202 mRNA transcripts regulated...</item><item key="geo_gse_id">E-GEOD-34511</item><item key="owner_profile">/profile/8773/arrayexpressuploader</item><item key="factor_count">1</item><item key="sample_count">2</item><item key="tags"><item>cancer</item><item>prostate</item><item>ventral</item></item><item key="lastmodified">Dec.12, 2014</item><item key="is_default">False</item><item key="geo_gds_id"/><item key="slug">mrna-profiling-by-androgen-induced-tumor-suppresso</item><item key="geo_id_plat">E-GEOD-34511_A-AFFY-45</item><item key="name">mRNA profiling by androgen-induced tumor suppressor U19/EAF2 in the mouse prostate U19/EAF2 knockout</item><item key="created">Nov.12, 2014</item><item key="summary">To elucidate potential mechanisms of U19/EAF2 action, we performed cDNA microarray analysis and identified 202 mRNA transcripts regulated by U19/EAF2 in the mouse ventral prostate. Of these transcripts, 167 are network eligible genes, with 63 associated with cancer and 24 with reproductive system diseases. Bioinformatics analysis indicated that U19/EAF2 knockout activates the RAS-BRAF-ERK signaling pathway, which is known to play important roles in carcinogenesis. prostate wild type and U19/EAF2 knockout</item><item key="source">http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-34511</item><item key="sample_source">http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-34511/samples/</item></data></biogps>
