{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSM850394": {"GENOTYPE": "U19/Eaf2 +/+"}}, {"GSM850395": {"GENOTYPE": "U19/Eaf2 -/-"}}], "id": 6720, "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "To elucidate potential mechanisms of U19/EAF2 action, we performed cDNA microarray analysis and identified 202 mRNA transcripts regulated...", "geo_gse_id": "E-GEOD-34511", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 2, "tags": ["cancer", "prostate", "ventral"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "mrna-profiling-by-androgen-induced-tumor-suppresso", "geo_id_plat": "E-GEOD-34511_A-AFFY-45", "name": "mRNA profiling by androgen-induced tumor suppressor U19/EAF2 in the mouse prostate U19/EAF2 knockout", "created": "Nov.12, 2014", "summary": "To elucidate potential mechanisms of U19/EAF2 action, we performed cDNA microarray analysis and identified 202 mRNA transcripts regulated by U19/EAF2 in the mouse ventral prostate. Of these transcripts, 167 are network eligible genes, with 63 associated with cancer and 24 with reproductive system diseases. Bioinformatics analysis indicated that U19/EAF2 knockout activates the RAS-BRAF-ERK signaling pathway, which is known to play important roles in carcinogenesis. prostate wild type and U19/EAF2 knockout", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-34511", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-34511/samples/"}