ArrayExpress Uploader0humanmiR-376a*A (24 h)miR-376a*A (24 h)miR-376a*A (24 h)miR-376a*G (24 h)miR-376a*G (24 h)miR-376a*G (24 h)control miRNA (24 h)control miRNA (24 h)control miRNA (24 h)4374arrayexpress_sid4Enforced expression of miRNAs in cells leads to down-regulation of several mRNAs which harbour binding sites in their 3'UTRs for the...E-GEOD-34454/profile/8773/arrayexpressuploader19Dec.12, 2014Falseexpression-data-from-transfection-of-sw1783-gliomaE-GEOD-34454_A-AFFY-44Expression data from transfection of SW1783 glioma cells with microRNA-376a* for 24 hoursSep.19, 2014Enforced expression of miRNAs in cells leads to down-regulation of several mRNAs which harbour binding sites in their 3'UTRs for the overexpressed miRNA and represent potential target genes of the miRNA We transfected unedited miR-376a* (376a*A) and edited miR-376a* (376a*G) into SW1783 cells to identify transcripts down-regulated by each in comparison to control miRNA transfection. The aim was to identify target genes subject to direct regulation by miR-376a*A and by miR-376a*G. SW1783 cells (100,000) were transfected with 50 nM of miR-376a*A, miR-376a*G or miR-control. Following incubation for 24 hours, total RNA was isolated from transfected cells. For each (miR-376a*A or miR-376a*G), genes differentially expressed upon miRNA transfection were determined based on comparison with miR-control-transfected samples. Biological triplicates were used for each sample type.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-34454http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-34454/samples/