{"platform": 4, "owner": "ArrayExpress Uploader", "ownerprofile_id": "arrayexpress_sid", "species": "human", "factors": [{"GSM841020": {"CELL TYPE": "CD133+  carcinoma cell"}}, {"GSM84102": {"CELL TYPE": "CD133-  carcinoma cell"}}, {"GSM841020": {"CELL TYPE": "CD133+  carcinoma cell"}}, {"GSM84102": {"CELL TYPE": "CD133-  carcinoma cell"}}, {"GSM841020": {"CELL TYPE": "CD133+  carcinoma cell"}}, {"GSM84102": {"CELL TYPE": "CD133-  carcinoma cell"}}, {"GSM841026": {"CELL TYPE": "carcinoma associated fibroblast"}}, {"GSM841026": {"CELL TYPE": "carcinoma associated fibroblast"}}, {"GSM841026": {"CELL TYPE": "carcinoma associated fibroblast"}}], "id": 4327, "pop_total": 0, "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-34053", "summary_wrapped": "CD133-positive colorectal cancer cells exhibit enhanced tumorigenicity over CD133-negative cells. The CD133+ cells are more interactive...", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 9, "tags": ["cancer", "carcinoma", "colorectal cancer"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "cd133-colon-cancer-cells-are-more-interactive-with", "geo_id_plat": "E-GEOD-34053_A-AFFY-44", "name": "CD133+ colon cancer cells are more interactive with the tumor microenvironment than CD133- cells", "created": "Sep.16, 2014", "summary": "CD133-positive colorectal cancer cells exhibit enhanced tumorigenicity over CD133-negative cells. The CD133+ cells are more interactive with and responsive to their stromal microenvironment because they also express the cognate receptors, such as CXCR4, for ligands produced by their neighboring carcinoma-associated fibroblasts, such as SDF-1 (stromal-derived growth factor). we isolated and separately cultured both the carcinoma cells and CAF from the same patient tumor.  Three samples (CD133+, CD133-, Carcinoma associated fibroblasts) in triplicate for a total of 9 samples.", "geo_gse_id": "E-GEOD-34053", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-34053/samples/"}