{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSM840332": {"VARIATION": "wild type, A2AR+/+FoxP3GFP"}}, {"GSM840332": {"VARIATION": "wild type, A2AR+/+FoxP3GFP"}}, {"GSM840334": {"VARIATION": "A2AR knockout (KO), A2AR-/-FoxP3GFP"}}, {"GSM840334": {"VARIATION": "A2AR knockout (KO), A2AR-/-FoxP3GFP"}}, {"GSM840332": {"VARIATION": "wild type, A2AR+/+FoxP3GFP"}}, {"GSM840332": {"VARIATION": "wild type, A2AR+/+FoxP3GFP"}}], "id": 6696, "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "The adenosine 2A receptor (A2AR) is expressed on regulatory T cells (Tregs), but the functional significance is currently unknown.  We...", "geo_gse_id": "E-GEOD-34006", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 6, "tags": ["lymph", "spleen"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "role-of-adenosine-2a-receptors-a2ar-on-regulatory", "geo_id_plat": "E-GEOD-34006_A-AFFY-45", "name": "Role of Adenosine 2A Receptors (A2AR) on regulatory T cells (Tregs)", "created": "Nov.12, 2014", "summary": "The adenosine 2A receptor (A2AR) is expressed on regulatory T cells (Tregs), but the functional significance is currently unknown.  We compared the gene expression between wild-type (WT) and A2AR knockout (KO) Tregs and between WT Tregs treated with vehicle or a selective A2AR agonist. FACS-sorted GFP positive Tregs from WT or A2AR KO FoxP3GFP mouse spleen and lymph nodes were incubated 18 hr with vehicle (DMSO), a separate set of WT Tregs were incubated with the selective A2AR agonist ATL1222 10 nM (Dogwood Pharmaceuticals, Inc.) for 18 hr prior to RNA isolation.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-34006", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-34006/samples/"}