{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSM840129": {"INFECTION": "no DT mock infected"}}, {"GSM840130": {"INFECTION": "no DT infected"}}, {"GSM84013": {"INFECTION": "plus DT mock infected"}}, {"GSM840132": {"INFECTION": "plus DT infected"}}], "id": 6694, "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "Dendritic cells (DCs) regulate both innate and adaptive immune responses. The role of CD11c-plus DCs in the corneal response to to herpes...", "geo_gse_id": "E-GEOD-33991", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 4, "tags": ["bone", "bone marrow", "dendritic", "diphtheria", "herpes simplex"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_id_plat": "E-GEOD-33991_A-AFFY-45", "slug": "early-responding-dendritic-cells-direct-local-natu", "geo_gds_id": "", "name": "Early responding dendritic cells direct local natural killer response to control HSV-1 infection within the cornea", "created": "Nov.12, 2014", "summary": "Dendritic cells (DCs) regulate both innate and adaptive immune responses. The role of CD11c-plus DCs in the corneal response to to herpes simplex virus-1 (HSV-1) infection was investigated by depleting them prior to infection. Bone marrow cells from CD11c-DTR (C.FVB-Tg(Itgax-DTR/EGFP)57Lan/J) mice were transferred intravenously to irradiated BALB/cJ host mice. After 6 weeks, the bone marrow chimeric host mice were injected with diphtheria toxin (DT) to deplete CD11c-positive cells. Two days after injection, the mice were subjected to a standard corneal infection protocol using HSV-1.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-33991", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-33991/samples/"}