ArrayExpress Uploaderarrayexpress_sidmousenormalfatnormalfatdiabeticfatdiabeticfatAAT treatedfatAAT treatedfatPower mix treatedfatPower mix treatedfatPower mix treatedfatnormalPLNsnormalPLNsnormalPLNsnormalPLNsdiabeticPLNsdiabeticPLNsAAT treatedPLNsAAT treatedPLNsAAT treatedPLNsAAT treatedPLNs669006To search for new therapeutic targets for type 1 & 2 diabetes, we have applied genome wide transcriptional profiling and systems biology...E-GEOD-33891/profile/8773/arrayexpressuploader219genomeglucoseinsulinlymphlymph nodepancreatic lymph nodeDec.12, 2014FalseE-GEOD-33891_A-AFFY-45the-role-for-tnf-alpha-in-murine-type-1-and-2-diabThe role for TNF-alpha in murine type 1 and 2 diabetesNov.12, 2014To search for new therapeutic targets for type 1 & 2 diabetes, we have applied genome wide transcriptional profiling and systems biology oriented bioinformatics analysis to examine the impact of the Power mix(PM) and Alpha-1 Anti-Trypsin( AAT) regimens upon pancreatic lymph node (PLN) and fat, a crucial tissue for insulin dependent glucose disposal, in new onset diabetic NOD mice. Transcriptional profiles of fat and PLNs in normal (non diabetic) NOD mice (NOR), new onset diabetic (DIA), new onset diabetic NOD mice treated with AAT or PM were perfromed in this studyhttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-33891http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-33891/samples/