ArrayExpress Uploaderarrayexpress_sidmousepurified spermatocytesWTpurified spermatocytesWTpurified spermatocytesWTpurified spermatocytesWTpurified spermatocytesGRTH nullpurified spermatocytesGRTH nullpurified spermatocytesGRTH nullpurified spermatocytesGRTH nullpurified round spermatidsWTpurified round spermatidsWTpurified round spermatidsWTpurified round spermatidsGRTH nullpurified round spermatidsGRTH nullpurified round spermatidsGRTH nullpurified Leydig cellsWTpurified Leydig cellsWTpurified Leydig cellsGRTH nullpurified Leydig cellsGRTH nulltesticular polysomeWTtesticular polysomeWTtesticular polysomeWTtesticular polysomeWTtesticular polysomeWTtesticular polysomeWTtesticular polysomeWTtesticular polysomeGRTH nulltesticular polysomeGRTH nulltesticular polysomeGRTH null668906The down-regulation of known genes concerned with spermatogenesis at polysomal sites in GRTH KO and their association with GRTH in WT...E-GEOD-33860/profile/8773/arrayexpressuploader228proteinDec.12, 2014Falseprofile-of-testicular-polysomal-gene-expression-reE-GEOD-33860_A-AFFY-45Profile of testicular polysomal gene expression regulated by Gonadotropin Regulated Testicular RNA helicase in adult miceNov.12, 2014The down-regulation of known genes concerned with spermatogenesis at polysomal sites in GRTH KO and their association with GRTH in WT coupled with early findings of minor or unchanged total mRNAs and abolition of their protein expression in KO, underscore the relevance of GRTH in translation. Studies showed the association of GRTH bound polysome genes with the ubiquitin-proteasome-heat shock protein signaling network pathway and NFκB/TP53/TGFB1 signaling networks were derived from the differentially expressed gene analysis. Microarray differential gene expression analysis was performed using polysome-bound RNA isolated from testes of wild type (WT) and GRTH KO mice.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-33860http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-33860/samples/