{"owner": "ArrayExpress Uploader", "ownerprofile_id": "arrayexpress_sid", "species": "mouse", "factors": [{"GSM838129": {"CELL TYPE": "purified spermatocytes", "VARIATION": "WT"}}, {"GSM838129": {"CELL TYPE": "purified spermatocytes", "VARIATION": "WT"}}, {"GSM838129": {"CELL TYPE": "purified spermatocytes", "VARIATION": "WT"}}, {"GSM838129": {"CELL TYPE": "purified spermatocytes", "VARIATION": "WT"}}, {"GSM838133": {"CELL TYPE": "purified spermatocytes", "VARIATION": "GRTH null"}}, {"GSM838133": {"CELL TYPE": "purified spermatocytes", "VARIATION": "GRTH null"}}, {"GSM838133": {"CELL TYPE": "purified spermatocytes", "VARIATION": "GRTH null"}}, {"GSM838133": {"CELL TYPE": "purified spermatocytes", "VARIATION": "GRTH null"}}, {"GSM838137": {"CELL TYPE": "purified round spermatids", "VARIATION": "WT"}}, {"GSM838137": {"CELL TYPE": "purified round spermatids", "VARIATION": "WT"}}, {"GSM838137": {"CELL TYPE": "purified round spermatids", "VARIATION": "WT"}}, {"GSM83814": {"CELL TYPE": "purified round spermatids", "VARIATION": "GRTH null"}}, {"GSM83814": {"CELL TYPE": "purified round spermatids", "VARIATION": "GRTH null"}}, {"GSM83814": {"CELL TYPE": "purified round spermatids", "VARIATION": "GRTH null"}}, {"GSM838145": {"CELL TYPE": "purified Leydig cells", "VARIATION": "WT"}}, {"GSM838145": {"CELL TYPE": "purified Leydig cells", "VARIATION": "WT"}}, {"GSM838148": {"CELL TYPE": "purified Leydig cells", "VARIATION": "GRTH null"}}, {"GSM838148": {"CELL TYPE": "purified Leydig cells", "VARIATION": "GRTH null"}}, {"GSM83815": {"CELL TYPE": "testicular polysome", "VARIATION": "WT"}}, {"GSM83815": {"CELL TYPE": "testicular polysome", "VARIATION": "WT"}}, {"GSM83815": {"CELL TYPE": "testicular polysome", "VARIATION": "WT"}}, {"GSM83815": {"CELL TYPE": "testicular polysome", "VARIATION": "WT"}}, {"GSM83815": {"CELL TYPE": "testicular polysome", "VARIATION": "WT"}}, {"GSM83815": {"CELL TYPE": "testicular polysome", "VARIATION": "WT"}}, {"GSM83815": {"CELL TYPE": "testicular polysome", "VARIATION": "WT"}}, {"GSM838158": {"CELL TYPE": "testicular polysome", "VARIATION": "GRTH null"}}, {"GSM838158": {"CELL TYPE": "testicular polysome", "VARIATION": "GRTH null"}}, {"GSM838158": {"CELL TYPE": "testicular polysome", "VARIATION": "GRTH null"}}], "id": 6689, "pop_total": 0, "platform": 6, "summary_wrapped": "The down-regulation of known genes concerned with spermatogenesis at polysomal sites in GRTH KO and their association with GRTH in WT...", "geo_gse_id": "E-GEOD-33860", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 28, "tags": ["protein"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "profile-of-testicular-polysomal-gene-expression-re", "geo_id_plat": "E-GEOD-33860_A-AFFY-45", "name": "Profile of testicular polysomal gene expression regulated by Gonadotropin Regulated Testicular RNA helicase in adult mice", "created": "Nov.12, 2014", "summary": "The down-regulation of known genes concerned with spermatogenesis at polysomal sites in GRTH KO and their association with GRTH in WT coupled with early findings of minor or unchanged total mRNAs and abolition of their protein expression in KO, underscore the relevance of GRTH in translation. Studies showed the association of GRTH bound polysome genes with the ubiquitin-proteasome-heat shock protein signaling network pathway and NF\u03baB/TP53/TGFB1 signaling networks were derived from the differentially expressed gene analysis. Microarray differential gene expression analysis was performed using polysome-bound RNA isolated from testes of wild type (WT) and GRTH KO mice.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-33860", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-33860/samples/"}