<?xml version="1.0" encoding="ASCII"?>
<biogps><data><item key="owner">ArrayExpress Uploader</item><item key="pop_total">0</item><item key="species">human</item><item key="factors"><item><item key="GSM835548"><item key="STATE">hyper-methylation</item><item key="CELL LINE">HeLa</item><item key="OVEREXPRESSION">mtTFB1</item></item></item><item><item key="GSM835548"><item key="STATE">hyper-methylation</item><item key="CELL LINE">HeLa</item><item key="OVEREXPRESSION">mtTFB1</item></item></item><item><item key="GSM835550"><item key="STATE">hyper-methylation</item><item key="CELL LINE">A1555G</item><item key="OVEREXPRESSION">not specified</item></item></item><item><item key="GSM835550"><item key="STATE">hyper-methylation</item><item key="CELL LINE">A1555G</item><item key="OVEREXPRESSION">not specified</item></item></item><item><item key="GSM835552"><item key="STATE">basal</item><item key="CELL LINE">HeLa</item><item key="OVEREXPRESSION">mtTFB1[G65A]</item></item></item><item><item key="GSM835552"><item key="STATE">basal</item><item key="CELL LINE">HeLa</item><item key="OVEREXPRESSION">mtTFB1[G65A]</item></item></item><item><item key="GSM835554"><item key="STATE">basal</item><item key="CELL LINE">A1555G</item><item key="OVEREXPRESSION">not specified</item></item></item><item><item key="GSM835554"><item key="STATE">basal</item><item key="CELL LINE">A1555G</item><item key="OVEREXPRESSION">not specified</item></item></item></item><item key="id">4311</item><item key="ownerprofile_id">arrayexpress_sid</item><item key="platform">4</item><item key="summary_wrapped">This dataset investigates the transcriptional effect of mitochondrial 12S rRNA hypermethylation, both by overexpressing the mitochondrial...</item><item key="geo_gse_id">E-GEOD-33780</item><item key="owner_profile">/profile/8773/arrayexpressuploader</item><item key="factor_count">3</item><item key="sample_count">8</item><item key="tags"><item>basal</item><item>cell</item></item><item key="lastmodified">Dec.12, 2014</item><item key="is_default">False</item><item key="geo_gds_id"/><item key="slug">mitochondrial-12s-hypermethylation-in-hela-cells-a</item><item key="geo_id_plat">E-GEOD-33780_A-AFFY-44</item><item key="name">Mitochondrial 12S hypermethylation in HeLa cells and A1555G cybrids</item><item key="created">Sep.16, 2014</item><item key="summary">This dataset investigates the transcriptional effect of mitochondrial 12S rRNA hypermethylation, both by overexpressing the mitochondrial methyltransferase mtTFB1 in HeLa cells and by using A1555G cybrids, where the 12S rRNA is hypermethylated. HeLa cells overexpressing a methyltransferase-deficient mtTFB1 (mtTFB1[G65A]) and wild-type A1555A cybrids were used as controls. four samples with 12S rRNA hypermethylation (two cell lines, with two biological replicates each) versus four samples with basal 12S rRNA methylation (two cell lines, with two biological replicates each)</item><item key="source">http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-33780</item><item key="sample_source">http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-33780/samples/</item></data></biogps>
