{"owner": "ArrayExpress Uploader", "ownerprofile_id": "arrayexpress_sid", "species": "human", "factors": [{"GSM833188": {"GENOTYPE/VARIATION": "RASv12 overexpression", "CELL TYPE": "senescent fibroblast"}}, {"GSM833188": {"GENOTYPE/VARIATION": "RASv12 overexpression", "CELL TYPE": "senescent fibroblast"}}, {"GSM833188": {"GENOTYPE/VARIATION": "RASv12 overexpression", "CELL TYPE": "senescent fibroblast"}}, {"GSM833185": {"GENOTYPE/VARIATION": "wild type", "CELL TYPE": "growing fibroblast"}}, {"GSM833185": {"GENOTYPE/VARIATION": "wild type", "CELL TYPE": "growing fibroblast"}}, {"GSM833185": {"GENOTYPE/VARIATION": "wild type", "CELL TYPE": "growing fibroblast"}}], "id": 1270, "pop_total": 0, "platform": 3, "summary_wrapped": "Senescence in WI-38 cell context was induce by RASv12 over expression Cellular senescence is a permanent cell cycle arrest that is...", "geo_gse_id": "E-GEOD-33710", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 6, "tags": ["cancer", "cell", "fibroblast", "line", "protein"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "transcriptomic-datat-of-senescence-wi-38-cell", "geo_id_plat": "E-GEOD-33710_A-AFFY-33", "name": "Transcriptomic datat of senescence WI-38 cell", "created": "Jun.18, 2014", "summary": "Senescence in WI-38 cell context was induce by RASv12 over expression Cellular senescence is a permanent cell cycle arrest that is triggered by cancer-  initiating or promoting events in mammalian cells and is now considered a major tumour suppressor mechanism. Here, we did a transcriptomic analysis and compared WI-38 contol wich is a human fibroblaste cell line and WI-38 that overexpressed RASv12  a G protein that induce senescence. The goal of our project is to compare transciptomic profile of human growing fibroblast (WI-38 control) and senescent human fibroblast (WI-38 OERAS) Comparaison WI-38 vs WI-38 OE RAS", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-33710", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-33710/samples/"}