{"owner": "ArrayExpress Uploader", "pop_total": 0, "id": 4296, "factors": [{"GSM827130": {"CELL LINE": "DU-145", "TREATMENT": "none"}}, {"GSM827130": {"CELL LINE": "DU-145", "TREATMENT": "none"}}, {"GSM827130": {"CELL LINE": "DU-145", "TREATMENT": "none"}}, {"GSM827133": {"CELL LINE": "DU-145", "TREATMENT": "converted to docetaxel-resistant cells"}}, {"GSM827133": {"CELL LINE": "DU-145", "TREATMENT": "converted to docetaxel-resistant cells"}}, {"GSM827133": {"CELL LINE": "DU-145", "TREATMENT": "converted to docetaxel-resistant cells"}}, {"GSM827136": {"CELL LINE": "PC3", "TREATMENT": "none"}}, {"GSM827136": {"CELL LINE": "PC3", "TREATMENT": "none"}}, {"GSM827136": {"CELL LINE": "PC3", "TREATMENT": "none"}}, {"GSM827139": {"CELL LINE": "PC3", "TREATMENT": "converted to docetaxel-resistant cells"}}, {"GSM827139": {"CELL LINE": "PC3", "TREATMENT": "converted to docetaxel-resistant cells"}}, {"GSM827139": {"CELL LINE": "PC3", "TREATMENT": "converted to docetaxel-resistant cells"}}], "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "Docetaxel-based chemotherapy is the standard first-line therapy in metastatic castration-resistant prostate cancer. However, most...", "pubmed_id": 22027694, "geo_gse_id": "E-GEOD-33455", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 12, "tags": ["cancer", "cell", "genome", "line", "prostate", "prostate cancer"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "expression-data-from-docetaxel-resistant-prostate", "geo_id_plat": "E-GEOD-33455_A-AFFY-44", "name": "Expression data from docetaxel-resistant prostate cancer cell lines", "created": "Sep.16, 2014", "summary": "Docetaxel-based chemotherapy is the standard first-line therapy in metastatic castration-resistant prostate cancer. However, most patients eventually develop resistance to this treatment. The aim of the study was to identify key molecular genes and networks associated with docetaxel resistance in 2 models of docetaxel-resistant castration-resistant prostate cancer cell lines. DU-145 and PC-3 cells were converted to docetaxel-resistant cells, DU-145R and PC-3R, respectively. Whole-genome arrays were used to compare global gene expression between these 4 cell lines. Arrays were performed by triplicate for each cell line.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-33455", "species": "human", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-33455/samples/"}