ArrayExpress Uploader0humannot applicablenot applicable71not applicableFunknownAdrenalectomy for metastatic lung carcinomaleftnot applicablenot applicableunknownMembraneunknownnot applicablenot applicable58not applicableFunknownAdrenalectomy for ACA; Conn's syndromerightnot applicablenot applicableunknownunknownunknownnot applicablenot applicable71not applicableMunknownAdrenalectomy for renal cell carcinomarightnot applicablenot applicableunknownunknownunknownnot applicablenot applicable44not applicableMunknownAdrenalectomy for ACA; Conn's syndromeleftnot applicablenot applicableunknownunknownunknownnot applicablenot applicable32not applicableFunknownAdrenalectomy for ACArightnot applicablenot applicableunknownMembraneunknownnot applicablenot applicable28not applicableMunknownAdrenalectomy for pheochromocytoma (Multiple Endocrine Neoplasia, Type IIA)leftnot applicablenot applicableunknownMembraneunknownnot applicablenot applicable55not applicableMunknownAdrenalectomy for multinodular cortical hyperplasia; Conn's syndromeleftnot applicablenot applicableunknownMembraneunknownnot applicablenot applicable78not applicableMunknownAdrenalectomy for renal cell carcinomaleftnot applicablenot applicableunknownunknownunknownnot applicablenot applicable41not applicableMunknownAdrenalectomy for renal cell carcinomaunknownnot applicablenot applicableunknownunknownunknownnot applicablenot applicable58not applicableMunknownAdrenalectomy for pheochromocytomaleftnot applicablenot applicableunknownunknownunknownnot applicable2.545not applicableFwild typeCushing syndromeleft12.1not applicableunknownMembraneunknownnot applicable3.528not applicableFwild typeCushing syndromeleft25.2not applicableunknownMembraneunknownnot applicable5.557not applicableFwild typeCushing syndromeright50not applicableunknownMembraneunknownnot applicable2.525not applicableFwild typeCushing syndromeright16not applicableunknownMembraneunknownnot applicable2.725not applicableFwild typeCushing syndromeleft11.1not applicableunknownMembraneunknownnot applicable2.256not applicableFwild typeHyperaldosteronismright8.2not applicableunknownMembraneunknownnot applicable1.133not applicableFwild typeHyperaldosteronismleft17.2not applicableunknownMembraneunknownnot applicableunknown44not applicableMwild typeAldosteronomaleft10.5not applicableunknownMembraneunknownnot applicable1.371not applicableFwild typeConn's syndromeleft8.5not applicableunknownMembraneunknownnot applicable1.556not applicableFwild typeLeft adrenal massleft7.6not applicableunknownMembraneunknownnot applicable2.551not applicableFwild typeAldosteronomaright4.95not applicableunknownMembraneunknownnot applicable532not applicableFwild typeHyperaldosteronismright14.9not applicableunknownMembraneunknownnot applicable2.538not applicableMwild typeHyperaldosteronismleft23.6not applicableunknownMembraneunknownnot applicable4.249not applicableFwild typeBilateral adrenal massesleft22.4not applicableunknownMembraneunknownnot applicable3.362not applicableFwild typehypertensionright65not applicableunknownNuclearunknownnot applicable759not applicableMwild typeRight adrenal massright95not applicableunknownNuclearunknownnot applicable6.252not applicableMmutantLeft adrenal massleft57not applicableunknownMembraneunknownnot applicable3.554not applicableFmutantRight pheochromocytomaright12.5not applicableunknownNuclearunknownnot applicable948not applicableMmutantabdominal painleft174.5not applicableunknownMembraneunknownnot applicable4.555not applicableMmutantCushing syndromeleft31not applicableunknownMembraneunknownnot applicable7.264not applicableFmutantRight adrenal massright116not applicableunknownMembraneunknownnot applicable5.545not applicableMmutantLeft adrenal massleft45not applicableunknownNuclearunknownHigh3.2<101FunknownVirilization and microcephalyright122212.46849315MembranealiveLowunknown494FunknownStatus post adrenalectomynot applicableunknown66.55MembranealiveHigh9452FunknownLeft adrenal massleft180241.512328767MembranedeadHighunknown484FunknownHistory of Adrenocortical carcinomanot applicableunknown511.657534247MembranedeadHighunknown774MunknownTumor of left hepatic lobenot applicableunknown451.202739726MembranedeadHigh16472FunknownLeft adrenal massleftunknown411.29MembranealiveLow5.5552MunknownCushing Syndrome; Left adrenalectomy 3 years prior for adrenocortical tumorleft35.14unknownMembraneunknownLow19522FunknownRight adrenal massright289022.780821918MembranedeadHigh9.2342Munknownunknownleft266740.775342466MembranedeadLow16354FunknownHistory of Adrenocortical carcinoma with lung, liver and bone metastises 1 year priorleft46081.232876712MembranedeadLow19522MunknownLeft adrenal massleft23101unknownMembraneunknownLow6.2482MunknownLeft adrenal massleft11045.56MembranealiveLow5452Munknownunknownleft6028.95MembranealiveHigh18393FunknownCushing syndromeleft9001090.090410959MembranedeadLow15.5403FunknownLeft adrenal massleftunknown9unknownMembraneunknownHigh12312FunknownLiver tumor; Severe abdominal painright5206515.12MembranealiveLow16.5872Funknownunknownleft1690.40unknownMembraneunknownHigh9454FunknownRight flank pain; Masses in right kidney, liver and both lungsrightunknown1370.120547945MembranedeadLow17413FunknownLeft adrenal massleft2540124.753424658MembranedeadHigh12<104MunknownIncreased testosteroneleft450640.476712329NucleardeadLow8.5322FunknownHyperaldosteronismright4007unknownNuclearunknownHigh15502MunknownLeft adrenal massleft36045unknownNuclearunknownLow10552FunknownHyperaldosteronismleft21215unknownNuclearunknownHigh10.5192MunknownLeft adrenal massleftunknown270.619178082NucleardeadHigh9.8612FunknownCushing syndromeright253270.942465753NucleardeadHigh13333FunknownCortisol secreting tumorleft66070unknownNuclearunknownLowunknown314FunknownHistory of Adrenocortical carcinomanot applicableunknown16unknownNuclearunknownHigh18.5602FunknownCushing syndromeright1805400.364383562NucleardeadHigh15.5513FunknownRight adrenal mass; elevated androgens and cortisolright1305232.232876712NucleardeadHigh22714MunknownRight adrenal tumor; Leg edemaright2440220.624657534NucleardeadHigh26254FunknownHistory of adrenal mass; 2 month history of abdominal painright2300340.898630137NucleardeadHighunknown471FunknownCushing Syndrome; Right adrenalectomy 4 years priorrightunknown377.81NuclearaliveHigh8.7492FunknownElevated serum aldosterone and DHEA-S; History of left nephrectomyleft39728unknownunknownunknown4291arrayexpress_sid4We scored adrenocortical carcinomas and adenomas for abnormal beta-catenin staining, and sequenced the beta-catenin gene in some samples....E-GEOD-33371/profile/8773/arrayexpressuploader1365adenomasadrenal cortexcortexDec.12, 2014Falsebeta-catenin-status-effects-in-human-adrenocorticaE-GEOD-33371_A-AFFY-44Beta-catenin status effects in human adrenocortical carcinomas (33), adenomas (22), and normal adrenal cortex (10)Sep.16, 2014We scored adrenocortical carcinomas and adenomas for abnormal beta-catenin staining, and sequenced the beta-catenin gene in some samples. We compared adrenocortincal carcinomas with and without abnormal beta-catenin staining and found many significant expression differences and significant results from enrichment testing. A similar comparison in the adenomas gave relatively few differences, and they did not correlate to differences found for the carcinomas. Abnormal beta-catenin staining was associated with mitotic rate and poorer patient survival in the carcinomas. In a second independent data set (given in a supplement) we again found beta-catenin associated with poor survival. The array data given is the same as GEO series GSE10927, with additional characteristics about beta-catenin, and new patient followup data. The analysis shown in a supplementary Excel file is also new. Human samples of 33 adrenocortical carcinomas, 22 adrenocortical adenomas, and 10 normal adrenal cortex samples, each from a different patient, had mRNA assays performed using Affymetrix HG_U133_plus_2 arrays, with 54675 probe-sets. 23 of the carcinomas were used in survival analysis. 27 additional samples without array data were also used in a survival analysis.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-33371http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-33371/samples/