{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSM798898": {"GENOTYPE/VARIATION": "wild type"}}, {"GSM798898": {"GENOTYPE/VARIATION": "wild type"}}, {"GSM798898": {"GENOTYPE/VARIATION": "wild type"}}, {"GSM798898": {"GENOTYPE/VARIATION": "wild type"}}, {"GSM798902": {"GENOTYPE/VARIATION": "E\u03bc-Myc transgenic"}}, {"GSM798902": {"GENOTYPE/VARIATION": "E\u03bc-Myc transgenic"}}, {"GSM798902": {"GENOTYPE/VARIATION": "E\u03bc-Myc transgenic"}}, {"GSM798902": {"GENOTYPE/VARIATION": "E\u03bc-Myc transgenic"}}, {"GSM798902": {"GENOTYPE/VARIATION": "E\u03bc-Myc transgenic"}}, {"GSM798902": {"GENOTYPE/VARIATION": "E\u03bc-Myc transgenic"}}, {"GSM798902": {"GENOTYPE/VARIATION": "E\u03bc-Myc transgenic"}}, {"GSM798902": {"GENOTYPE/VARIATION": "E\u03bc-Myc transgenic"}}, {"GSM798902": {"GENOTYPE/VARIATION": "E\u03bc-Myc transgenic"}}, {"GSM798902": {"GENOTYPE/VARIATION": "E\u03bc-Myc transgenic"}}, {"GSM798902": {"GENOTYPE/VARIATION": "E\u03bc-Myc transgenic"}}, {"GSM798902": {"GENOTYPE/VARIATION": "E\u03bc-Myc transgenic"}}, {"GSM798902": {"GENOTYPE/VARIATION": "E\u03bc-Myc transgenic"}}, {"GSM798902": {"GENOTYPE/VARIATION": "E\u03bc-Myc transgenic"}}, {"GSM798902": {"GENOTYPE/VARIATION": "E\u03bc-Myc transgenic"}}, {"GSM798902": {"GENOTYPE/VARIATION": "E\u03bc-Myc transgenic"}}, {"GSM798902": {"GENOTYPE/VARIATION": "E\u03bc-Myc transgenic"}}, {"GSM798902": {"GENOTYPE/VARIATION": "E\u03bc-Myc transgenic"}}], "id": 8274, "ownerprofile_id": "arrayexpress_sid", "platform": 7, "summary_wrapped": "The ability of oncogenes to provoke cancer is harnessed by regulators that control cell proliferation or induce apoptosis, and bypass of...", "geo_gse_id": "E-GEOD-32239", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 22, "tags": ["cancer", "cell", "lymphoma", "ribosome"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "gene-expression-profiling-of-myc-induced-lymphomag", "geo_id_plat": "E-GEOD-32239_A-AFFY-23", "name": "Gene Expression profiling of Myc-induced lymphomagenesis", "created": "Nov.23, 2014", "summary": "The ability of oncogenes to provoke cancer is harnessed by regulators that control cell proliferation or induce apoptosis, and bypass of these checkpoints is a hallmark of malignancies. Myc oncoproteins are overexpressed in ~70% of all cancers and induce numerous transcription targets that regulate cell growth, metabolism, and the ribosome machinery. We used the E\u03bc-Myc mouse model from which one can directly compare expression profiles of wild type versus Myc-expressing B220+ pre-malignant lymphocytes and also queried differences in gene expression that ensue following the neoplastic switch to lymphoma (Nilsson et al., 2005 - PMID:15894264 and Keller et al. 2010 - PMID:20598117). Wild type and precancerous E\u03bc-Myc transgenic B cells (from 4-6 week old littermates), and lymphomas from 13 independent  E\u03bc-Myc mice  were investigated.  These samples were used for subsequent RNA purification, labeling and hybridization to MOE430A Affymetrix arrays.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-32239", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-32239/samples/"}