Dataset: Expression data from breast cancer FNA and surgical specimens from patients

The behavior of breast cancers and their response to neoadjuvant systemic therapy depend on their phenotype which is to a large extent...

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The behavior of breast cancers and their response to neoadjuvant systemic therapy depend on their phenotype which is to a large extent determined by gene expression programs within the cancer cell. The purpose of the analysis was to compare matched gene expression profiles of pretreatment cancer with post-neoadjuvant systemic therapy, residual cancer. Pre-treatment FNA from primary tumors or post-treatment surgical specimens were obtained and RNA extracted and hybridized to afymetrix microarrays according to manufacturer protocol.

Species:: human
Samples:: 50
Source:: E-GEOD-32072
PubMed:: 22235097
Updated:: Dec.12, 2014
Registered:: Jun.18, 2014

Factors: (via ArrayExpress)

Sample	ORGANISM PART	TREATMENT	MOLECULAR SUBTYPE	PREPOST-PAIR	ER STATUS	HER2 STATUS
GSM795284	breast cancer surgical specimen	No Treatment	basal	26	ERneg	HER2neg
GSM795283	breast cancer surgical specimen	No Treatment	LumA	25	ERpos	HER2neg
GSM795282	breast cancer surgical specimen	No Treatment	LumA	24	ERpos	HER2neg
GSM79528	breast cancer surgical specimen	post-neoadjuvant systemic therapy	normal	23	ERneg	HER2neg
GSM795280	breast cancer surgical specimen	post-neoadjuvant systemic therapy	basal	22	ERneg	HER2neg
GSM795279	breast cancer surgical specimen	post-neoadjuvant systemic therapy	basal	20	ERneg	HER2neg
GSM795278	breast cancer surgical specimen	post-neoadjuvant systemic therapy	basal	19	ERneg	HER2neg
GSM795277	breast cancer surgical specimen	post-neoadjuvant systemic therapy	Her2	18	ERneg	HER2pos
GSM795276	breast cancer surgical specimen	No Treatment	basal	17	ERneg	HER2neg
GSM795275	breast cancer surgical specimen	post-neoadjuvant systemic therapy	LumA	16	ERpos	HER2neg
GSM795274	breast cancer surgical specimen	post-neoadjuvant systemic therapy	normal	15	ERpos	HER2neg
GSM795273	breast cancer surgical specimen	post-neoadjuvant systemic therapy	normal	14	ERpos	HER2neg
GSM795272	breast cancer surgical specimen	post-neoadjuvant systemic therapy	LumA	13	ERpos	HER2neg
GSM79527	breast cancer surgical specimen	post-neoadjuvant systemic therapy	basal	12	ERneg	HER2neg
GSM795270	breast cancer surgical specimen	post-neoadjuvant systemic therapy	basal	11	ERneg	HER2neg
GSM795269	breast cancer surgical specimen	post-neoadjuvant systemic therapy	basal	10	ERneg	HER2neg
GSM795268	breast cancer surgical specimen	post-neoadjuvant systemic therapy	normal	9	ERpos	HER2neg
GSM795267	breast cancer surgical specimen	post-neoadjuvant systemic therapy	normal	8	ERneg	HER2pos
GSM795266	breast cancer surgical specimen	post-neoadjuvant systemic therapy	LumB	7	ERpos	HER2neg
GSM795265	breast cancer surgical specimen	post-neoadjuvant systemic therapy	LumA	6	ERpos	HER2neg
GSM795264	breast cancer surgical specimen	post-neoadjuvant systemic therapy	normal	5	ERneg	HER2neg
GSM795263	breast cancer surgical specimen	post-neoadjuvant systemic therapy	normal	4	ERneg	HER2neg
GSM795262	breast cancer surgical specimen	post-neoadjuvant systemic therapy	LumA	3	ERpos	HER2neg
GSM79526	breast cancer surgical specimen	post-neoadjuvant systemic therapy	LumA	2	ERpos	HER2neg
GSM795260	breast cancer tumor	post-neoadjuvant systemic therapy	basal	1	ERneg	HER2pos
GSM795259	breast cancer tumor	No Treatment	basal	26	ERneg	HER2neg
GSM795258	breast cancer tumor	No Treatment	LumA	25	ERpos	HER2neg
GSM795257	breast cancer tumor	No Treatment	LumA	24	ERpos	HER2neg
GSM795256	breast cancer tumor	pre-neoadjuvant systemic therapy	normal	23	ERneg	HER2neg
GSM795255	breast cancer tumor	pre-neoadjuvant systemic therapy	basal	22	ERneg	HER2neg
GSM795254	breast cancer tumor	pre-neoadjuvant systemic therapy	basal	20	ERpos	HER2neg
GSM795253	breast cancer tumor	pre-neoadjuvant systemic therapy	basal	19	ERneg	HER2neg
GSM795252	breast cancer tumor	pre-neoadjuvant systemic therapy	Her2	18	ERneg	HER2pos
GSM79525	breast cancer tumor	No Treatment	basal	17	ERneg	HER2neg
GSM795250	breast cancer tumor	pre-neoadjuvant systemic therapy	LumA	16	ERpos	HER2neg
GSM795249	breast cancer tumor	pre-neoadjuvant systemic therapy	LumA	15	ERpos	HER2neg
GSM795248	breast cancer tumor	pre-neoadjuvant systemic therapy	basal	14	ERneg	HER2neg
GSM795247	breast cancer tumor	pre-neoadjuvant systemic therapy	LumA	13	ERpos	HER2neg
GSM795246	breast cancer tumor	pre-neoadjuvant systemic therapy	basal	12	ERneg	HER2neg
GSM795245	breast cancer tumor	pre-neoadjuvant systemic therapy	normal	11	ERneg	HER2neg
GSM795244	breast cancer tumor	pre-neoadjuvant systemic therapy	basal	10	ERneg	HER2neg
GSM795243	breast cancer tumor	pre-neoadjuvant systemic therapy	LumA	9	ERpos	HER2neg
GSM795242	breast cancer tumor	pre-neoadjuvant systemic therapy	basal	8	ERneg	HER2pos
GSM79524	breast cancer tumor	pre-neoadjuvant systemic therapy	Her2	7	ERpos	HER2neg
GSM795240	breast cancer tumor	pre-neoadjuvant systemic therapy	LumA	6	ERpos	HER2neg
GSM795239	breast cancer tumor	pre-neoadjuvant systemic therapy	Her2	5	ERneg	HER2pos
GSM795238	breast cancer tumor	pre-neoadjuvant systemic therapy	basal	4	ERneg	HER2neg
GSM795237	breast cancer tumor	pre-neoadjuvant systemic therapy	LumA	3	ERpos	HER2neg
GSM795236	breast cancer tumor	pre-neoadjuvant systemic therapy	LumA	2	ERpos	HER2neg
GSM795235	breast cancer tumor	pre-neoadjuvant systemic therapy	basal	1	ERneg	HER2neg