{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSM788456": {"CELL LINE": "MDA-MB231", "JMJD6 EXPRESSION": "Knock-down"}}, {"GSM788457": {"CELL LINE": "MDA-MB231", "JMJD6 EXPRESSION": "Control (scrambled siRNA)"}}, {"GSM788456": {"CELL LINE": "MDA-MB231", "JMJD6 EXPRESSION": "Knock-down"}}, {"GSM788457": {"CELL LINE": "MDA-MB231", "JMJD6 EXPRESSION": "Control (scrambled siRNA)"}}, {"GSM788456": {"CELL LINE": "MDA-MB231", "JMJD6 EXPRESSION": "Knock-down"}}, {"GSM788457": {"CELL LINE": "MDA-MB231", "JMJD6 EXPRESSION": "Control (scrambled siRNA)"}}, {"GSM788456": {"CELL LINE": "MDA-MB231", "JMJD6 EXPRESSION": "Knock-down"}}, {"GSM788457": {"CELL LINE": "MDA-MB231", "JMJD6 EXPRESSION": "Control (scrambled siRNA)"}}, {"GSM788464": {"CELL LINE": "MCF-7", "JMJD6 EXPRESSION": "Knock-down"}}, {"GSM788465": {"CELL LINE": "MCF-7", "JMJD6 EXPRESSION": "Control (scrambled siRNA)"}}, {"GSM788464": {"CELL LINE": "MCF-7", "JMJD6 EXPRESSION": "Knock-down"}}, {"GSM788465": {"CELL LINE": "MCF-7", "JMJD6 EXPRESSION": "Control (scrambled siRNA)"}}, {"GSM788464": {"CELL LINE": "MCF-7", "JMJD6 EXPRESSION": "Knock-down"}}, {"GSM788465": {"CELL LINE": "MCF-7", "JMJD6 EXPRESSION": "Control (scrambled siRNA)"}}, {"GSM788464": {"CELL LINE": "MCF-7", "JMJD6 EXPRESSION": "Knock-down"}}, {"GSM788465": {"CELL LINE": "MCF-7", "JMJD6 EXPRESSION": "Control (scrambled siRNA)"}}, {"GSM788472": {"CELL LINE": "MCF-7", "JMJD6 EXPRESSION": "Over-expressed"}}, {"GSM788472": {"CELL LINE": "MCF-7", "JMJD6 EXPRESSION": "Over-expressed"}}, {"GSM788472": {"CELL LINE": "MCF-7", "JMJD6 EXPRESSION": "Over-expressed"}}, {"GSM788475": {"CELL LINE": "MCF-7", "JMJD6 EXPRESSION": "Control (empty vector)"}}, {"GSM788472": {"CELL LINE": "MCF-7", "JMJD6 EXPRESSION": "Over-expressed"}}, {"GSM788472": {"CELL LINE": "MCF-7", "JMJD6 EXPRESSION": "Over-expressed"}}, {"GSM788472": {"CELL LINE": "MCF-7", "JMJD6 EXPRESSION": "Over-expressed"}}, {"GSM788475": {"CELL LINE": "MCF-7", "JMJD6 EXPRESSION": "Control (empty vector)"}}, {"GSM788472": {"CELL LINE": "MCF-7", "JMJD6 EXPRESSION": "Over-expressed"}}, {"GSM788472": {"CELL LINE": "MCF-7", "JMJD6 EXPRESSION": "Over-expressed"}}, {"GSM788472": {"CELL LINE": "MCF-7", "JMJD6 EXPRESSION": "Over-expressed"}}, {"GSM788475": {"CELL LINE": "MCF-7", "JMJD6 EXPRESSION": "Control (empty vector)"}}], "id": 4221, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "By survival analysis of breast cancer patients, JMJD6 was found to be significantly associated with poor prognosis. Over-expression and...", "geo_gse_id": "E-GEOD-31782", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 28, "tags": ["breast", "breast cancer", "cancer", "cell"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "knock-down-and-over-expression-of-jmjd6-in-mcf-7-a", "geo_id_plat": "E-GEOD-31782_A-AFFY-44", "name": "Knock-down and Over-expression of JMJD6 in MCF-7 and/or MDA-MB231", "created": "Sep.16, 2014", "summary": "By survival analysis of breast cancer patients, JMJD6 was found to be significantly associated with poor prognosis. Over-expression and knock-down of JMJD6 in breast cancer cell lines suggested a role in proliferation. In order to study the transcriptional events that occur following JMJD6 expression changes, siRNA-mediated knock-down of JMJD6 was performed in MCF-7 and MDA-MB231 and stable over-expression of JMJD6 was performed in MCF-7. There are 2 different siRNA-mediated knock-downs of JMJD6 with 2 biological replicates in MCF-7 and MDA-MB231; 3 clones of JMJD6 over-expression with 3 biological replicates in MCF-7. The control for the knock-downs is scrambled siRNA-treated MCF-7 and MDA-MB231 and the control for JMJD6 over-expression is empty vector over-expression in MCF-7.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-31782", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-31782/samples/"}