{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSM78498": {"CELL TYPE": "neurosphere, embryonic ganglionic eminence (GE)-derived"}}, {"GSM784982": {"CELL TYPE": "fibroblast"}}, {"GSM784983": {"CELL TYPE": "iPS cells"}}, {"GSM784984": {"CELL TYPE": "neurosphere, primary, iPS-derived"}}, {"GSM784985": {"CELL TYPE": "neurosphere, secondary, iPS-derived"}}, {"GSM784988": {"CELL TYPE": "ES cells"}}, {"GSM784989": {"CELL TYPE": "neurosphere, primary, ES-derived"}}, {"GSM784990": {"CELL TYPE": "neurosphere, secondary, ES-derived"}}], "id": 6602, "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "Recent reports have emphasized the pitfalls of iPSC technology including the potential for immunogenicity of transplanted cells. It is...", "geo_gse_id": "E-GEOD-31725", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 8, "tags": ["cell", "eminence", "fibroblast", "line"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "comparison-between-mouse-esips-derived-neurosphere", "geo_id_plat": "E-GEOD-31725_A-AFFY-45", "name": "Comparison between mouse ES/iPS derived neurosphere and mouse primary culture of neurospheres obtained from fetal mouse ganglionic eminence", "created": "Nov.11, 2014", "summary": "Recent reports have emphasized the pitfalls of iPSC technology including the potential for immunogenicity of transplanted cells. It is serious safety-related concern for iPSC-based cell therapy. However, preclinical data supporting the safety and efficacy of iPSCs are also accumulating. To address the concern of immunogenicity of ESCs/iPSCs or ESCs/iPSCs-derived neurospheres, global gene expression profiles were compared between undifferentiated mouse ESCs (EB3 line), mouse iPSCs (38C2 line), and ESC/iPSC-derived neurosphere and mouse primary culture of neurosphere obtained from fetal mouse ganglionic eminence. Mouse adult sklin fibroblast was used as a control. We used affymetrix microarrays to compare the global gene expression of neurospheres prepared several origins.  Keywords: Expression profiling by array RNA extracted from neurospheres was hybridized to Affymetrix microarrays.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-31725", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-31725/samples/"}