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Home › Dataset Library › Combination of a novel gene expression signature with a clinical nomogram improves the prediction of survival in high-risk bladder cancer  

Dataset: Combination of a novel gene expression signature with a clinical nomogram improves the prediction of survival in high-risk bladder cancer  

Urothelial carcinoma of the bladder is characterized by significant variability in clinical outcomes depending on stage and grade. The...

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Urothelial carcinoma of the bladder is characterized by significant variability in clinical outcomes depending on stage and grade. The addition of molecular information may improve our understanding of such heterogeneity and enhance prognostic prediction. The purpose of this study was to validate and improve published prognostic signatures for high-risk bladder cancer. We evaluated microarray data from 93 bladder cancer patients managed by radical cystectomy to determine gene expression patterns associated with clinical and prognostic variables.

Species:
human

Samples:
93

Source:
E-GEOD-31684

PubMed:
22228636

Updated:
Dec.12, 2014

Registered:
Sep.16, 2014


Factors: (via ArrayExpress)
Sample LAST KNOWN STATUS AGE AT RC PLND RESULT MONTHS DOD SEX CLUSTER PREOPCLINSTAGE NOMOGRAM SCORE SMOKINGPACK-YEARS CHEMO SMOKING POSTCHEMO TYPE STAGE RC GRADE RECURRENCE FREE SURVIVAL MONTHS (DISTANT AND LOCAL) HISTOLOGY
GSM78649 DOC 64.06 Negative 103.7864 No male 2.0 T3 81.44001734 20 No Former not specified pT2 High 103.7864 TCC
GSM786492 DOD 62.14 Negative 13.17454 Yes male 2.0 T2 81.71198473 not specified No Never salvage pT2 High 7.129363 TCC
GSM786493 DOD 65.96 Negative 19.77823 Yes female 1.0 T2 79.95740897 80 No Current not specified pT2 High 10.38193 TCC
GSM786494 DOD 56.1 Positive 16.4271 Yes male 2.0 T2 11.08510015 35 No Former not specified pT4 High 15.54004 TCC
GSM786495 DOC 68.0 Negative 13.14168 No female 1.0 T3 49.06355452 20 No Former not specified pT4 High 13.14168 TCC/CIS
GSM786496 DOD 69.93 Nx 4.435318 Yes male 1.0 T2 41.39963921 50 No Former not specified pT3 High 2.726899 TCC
GSM786497 DOC 65.0 Positive 87.85216 No male 2.0 T2 50.12822813 50 No Current not specified pT1 High 87.85216 TCC
GSM786498 NED 69.44 Negative 173.4045 No male 2.0 T1 64.48725601 not specified No Never not specified pT3 High 173.4045 TCC/CIS
GSM786499 DOD 47.47 Negative 108.4517 Yes male 1.0 T2 76.49581054 30 No Former salvage pT2 High 96.16427 TCC
GSM786500 DOC 77.9 Nx 175.5072 No female 2.0 T2 52.61069907 20 No Former not specified pT3 High 175.5072 TCC
GSM78650 NED 66.56 Negative 167.655 No male 1.0 T1 90.1987881 not specified No Never not specified pT1 Low 167.655 TCC
GSM786502 DOD 65.11 Negative 102.7023 Yes male 2.0 T1 40.62923558 not specified No Never not specified pT2 High 99.97536 TCC
GSM786503 DOC 76.93 Negative 0.3942505 No male 2.0 T2 61.80483246 45 No Former not specified pT3 High 0.3942505 TCC/Squamous
GSM786504 DOD 68.04 Positive 10.84189 Yes male 2.0 T2 1.0 80 No Former adjuvant pT4 High 7.326489 TCC
GSM786505 DOC 68.03 Negative 3.12115 No female 2.0 T1 47.79618735 40 No Current not specified pT4 High 3.12115 TCC/Squamous
GSM786506 DOD 72.77 Positive 3.351129 Yes male 2.0 T2 21.52250158 120 No Current not specified pT3 High 1.741273 TCC
GSM786507 NED 59.65 Positive 0.6570842 No female 1.0 T1 28.61319836 20 No Former not specified pT3 High 0.6570842 TCC
GSM786508 DOD 51.33 Negative 11.72895 Yes male 2.0 T2 69.75442714 10 No Former adjuvant pT3 High 8.312115 TCC
GSM786509 NED 73.32 Nx 31.31006 No male 2.0 T2 25.40171907 10 No Current not specified pT2 High 31.31006 TCC
GSM786510 DOD 56.61 Positive 8.213552 Yes male 1.0 T3 8.270066426 35 Yes Former salvage pT4 High 3.351129 TCC
GSM7865 DOC 78.08 Positive 24.67351 No male 2.0 T2 4.925223883 120 No Former not specified pT4 High 24.67351 TCC
GSM786512 DOD 68.75 Positive 13.30595 Yes male 2.0 T2 1.0 5 No Former salvage pT3 High 8.11499 TCC
GSM786513 DOC 69.49 Nx 1.084189 No male 2.0 T2 36.09372092 unk No Former not specified pT4 High 1.084189 TCC
GSM786514 DOD 62.08 Positive 7.326489 Yes male 2.0 T3 9.672482387 10 No Former adjuvant pT4 High 4.468172 TCC
GSM786515 DOC 72.72 Negative 3.285421 No female 1.0 T2 60.78974289 not specified No Never not specified pT3 High 3.285421 TCC
GSM786516 DOD 72.4 Nx 14.423 Yes female 1.0 T2 34.37579285 60 No Former salvage pT4 High 8.246407 TCC
GSM786517 NED 59.39 Negative 56.93634 No male 1.0 T1 81.96959756 not specified No Never not specified pT1 High 56.93634 TCC
GSM786518 DOD 74.61 Positive 58.31622 Yes male 2.0 T3 21.96386456 60 No Current salvage pT3 High 8.344969 TCC
GSM786519 DOD 58.15 Positive 4.960986 Yes male 2.0 T2 17.30881569 70 No Former not specified pT3 High 2.89117 TCC
GSM786520 DOD 52.99 Negative 9.297741 Yes female 2.0 T2 46.67259699 unk No Former salvage pT4 High 2.004107 TCC/Squamous
GSM78652 DOD 64.53 Positive 12.64887 Yes male nan T2 9.39539484 5 No Former adjuvant pT4 High 11.03901 TCC
GSM786522 NED 56.47 Negative 72.54209 No male 2.0 T2 67.59430251 60 No Current adjuvant pT3 High 72.54209 TCC/Squamous
GSM786523 DOD 73.42 Negative 90.1191 Yes male 1.0 T2 89.88210291 10 No Former not specified pTa Low 90.1191 TCC
GSM786524 DOD 68.35 Negative 19.58111 Yes male 2.0 T1 64.33773142 60 No Former adjuvant pT3 High 12.9117 TCC
GSM786525 DOC 68.72 Positive 5.322382 No female 2.0 Ta 1.0 90 No Current not specified pT4 High 5.322382 TCC
GSM786526 NED 84.48 Nx 3.383984 No male 2.0 T2 38.24540238 40 No Former not specified pT3 High 3.383984 TCC
GSM786527 DOC 75.32 Negative 91.17043 No female 1.0 T1 76.02888814 60 No Current not specified pTa High 91.17043 TCC
GSM786528 DOC 91.08 Nx 2.825462 No female 2.0 T2 31.81022665 50 No Former not specified pT3 High 2.825462 TCC
GSM786529 DOD 57.33 Positive 27.59754 Yes male 1.0 T1 22.16502989 not specified No Never adjuvant pT3 High 22.37372 TCC
GSM786530 DOD 77.0 NX 9.921971 Yes female 2.0 T2 46.44766646 40 No Former salvage pT3 High 6.899384 TCC
GSM78653 DOC 80.66 Negative 102.6366 No male 1.0 T2 43.10781602 60 No Former not specified pT3 High 102.6366 TCC
GSM786532 DOD 74.92 Positive 3.318275 Yes female 2.0 T2 23.81320156 58 No Former salvage pT3 High 1.544148 TCC
GSM786533 DOD 75.2 Negative 110.1273 Yes male 1.0 T2 59.59072639 30 No Former salvage pT3 High 6.767967 TCC
GSM786534 NED 88.5 Nx 105.7906 No male 1.0 T1 69.0645029 not specified No Never not specified pT1 High 105.7906 TCC
GSM786535 DOC 69.75 Positive 5.585216 No male 1.0 T2 20.65263972 40 No Former not specified pT3 High 5.585216 TCC
GSM786536 DOD 89.46 Nx 7.655031 Yes male 2.0 T3 15.38748125 10 No Former not specified pT4 High 6.045175 TCC
GSM786537 DOD 53.0 Negative 17.01848 Yes female 2.0 T2 82.51542593 unk No Former not specified pT2 High 16.29569 TCC
GSM786538 DOC 80.4 Negative 64.39425 No male 2.0 T1 68.97142268 not specified No Never not specified pT2 High 64.39425 TCC
GSM786539 NED 66.03 Negative 120.7721 No female 1.0 T2 54.14254844 25 No Current not specified pTa High 120.7721 TCC
GSM786540 NED 55.56 Positive 44.68172 No male 1.0 T3 12.38708981 30 No Current adjuvant pT4 High 44.68172 TCC
GSM78654 DOC 78.05 Negative 91.66324 No male 1.0 Ta 82.52366144 10 No Former not specified pTa High 91.66324 TCC
GSM786542 DOD 68.7 Positive 4.435318 Yes female 1.0 T2 6.797760997 not specified No Never salvage pT4 High 3.909651 TCC
GSM786543 DOC 61.14 Negative 79.44148 No male 2.0 T2 68.60720905 not specified No Never not specified pT3 High 79.44148 TCC/Squamous
GSM786544 DOD 79.39 Positive 13.66735 Yes female 1.0 T2 20.63742433 5 No Former salvage pT3 High 2.529774 TCC
GSM786545 DOC 84.11 Nx 65.28131 No female 1.0 T2 4.814475736 50 No Former not specified pT3 High 65.28131 TCC
GSM786546 DOD 83.63 Nx 0.788501 Yes male 1.0 T2 23.17374223 30 No Former not specified pT4 High 0.788501 TCC
GSM786547 DOD 71.91 Positive 13.47023 Yes male 1.0 T2 22.55107049 40 No Former salvage pT3 High 1.379877 TCC
GSM786548 DOC 74.68 Negative 109.3717 No male 1.0 T1 76.89741603 100 No Former not specified pT2 High 109.3717 TCC
GSM786549 NED 60.47 Negative 111.4415 Yes male 1.0 T2 67.28948158 not specified No Never salvage pT3 High 15.34292 TCC
GSM786550 DOD 81.49 Negative 9.823409 Yes male nan T2 57.4680497 60 No Former not specified pT3 High 9.002053 TCC
GSM78655 NED 67.33 Negative 102.5708 No female 2.0 T2 66.05294322 not specified No Never adjuvant pT3 High 102.5708 TCC
GSM786552 DOC 84.02 Negative 7.786448 No male 1.0 T2 46.60077495 40 No Former not specified pT3 High 7.786448 TCC
GSM786553 NED 69.17 Positive 101.8809 No male 2.0 T2 1.0 55 No Former adjuvant pT4 High 101.8809 TCC
GSM786554 DOC 72.87 Negative 32.62423 No male 1.0 T2 14.52217463 120 No Current not specified pT3 High 32.62423 TCC
GSM786555 DOC 62.44 Negative 3.449692 No male 1.0 T1 90.70677037 30 No Former not specified pT1 Low 3.449692 TCC
GSM786556 NED 57.37 Negative 79.6386 No male 1.0 Ta 92.15448049 unk No Former not specified pTa Low 79.6386 TCC
GSM786557 DOC 81.5 Negative 103.8522 No male 2.0 T2 10.62897531 25 No Current not specified pT3 High 103.8522 TCC
GSM786558 NED 72.61 NX 100.9938 No female 1.0 Ta 54.02532403 15 No Former not specified pT1 Low 100.9938 TCC
GSM786559 NED 85.09 Negative 91.46612 No female 1.0 Ta 79.17928416 5 No Former not specified pT1 High 91.46612 TCC
GSM786560 NED 74.09 Negative 98.16838 No male 2.0 T2 62.55822553 20 No Former adjuvant pT3 High 98.16838 TCC
GSM78656 DOC 78.82 Negative 15.08008 No male 2.0 T3 27.19682582 30 No Former not specified pT4 high 15.08008 TCC
GSM786562 DOC 67.15 Negative 6.63655 No male 2.0 T2 39.56057988 10 No Former not specified pT2 High 6.63655 TCC
GSM786563 DOD 74.75 Negative 12.71458 Yes male 1.0 T2 60.56478669 not specified No Never salvage pT3 High 6.702259 TCC
GSM786564 DOC 66.19 Negative 67.25257 No male 1.0 T2 17.62653309 40 No Former not specified pT3 High 67.25257 TCC
GSM786565 NED 57.72 Negative 42.87474 No male 1.0 Ta 67.08968299 30 No Current not specified pT1 Low 42.87474 TCC
GSM786566 DOC 78.51 Nx 51.94251 No male 2.0 T1 61.38268162 80 No Former not specified pT2 High 51.94251 TCC
GSM786567 DOD 61.87 Negative 15.01437 Yes male 1.0 T1 42.10907773 not specified no Never salvage pT2 High 4.862423 TCC
GSM786568 NED 69.63 Positive 84.73101 No male 1.0 T3 21.11155867 30 No Current not specified pT3 High 84.73101 TCC
GSM786569 NED 72.75 Positive 84.56674 No female 2.0 T1 10.61219835 80 No Current adjuvant pT3 High 84.56674 TCC
GSM786570 DOD 80.46 Nx 17.60986 Yes male 1.0 T2 38.72907066 90 No Former not specified pT3 High 16.26283 TCC
GSM78657 NED 41.73 Negative 85.94661 No female 1.0 T2 71.59866128 30 No Current adjuvant pT3 High 85.94661 TCC
GSM786572 NED 74.82 Negative 89.10062 No male 1.0 Ta 81.6631288 55 No Former not specified pT1 High 89.10062 TCC
GSM786573 NED 58.21 Negative 81.11704 No male 1.0 Ta 43.42879365 60 No Former not specified pT2 High 81.11704 TCC
GSM786574 NED 51.33 Negative 42.71047 No male 1.0 T1 82.3851487 not specified No Never not specified pT2 High 42.71047 TCC
GSM786575 NED 50.67 Positive 33.60986 No male 2.0 T1 11.91711954 40 No Former adjuvant pT4 High 33.60986 TCC
GSM786576 DOD 47.85 Negative 11.66324 Yes male 1.0 T2 61.61975413 80 Yes Current salvage pT3 High 6.340862 TCC
GSM786577 DOD 68.14 Negative 32.85421 Yes female 2.0 T3 65.92170237 not specified No Never salvage pT3 High 11.53183 TCC
GSM786578 DOD 82.72 Positive 11.82752 Yes male 1.0 T1 9.757349648 40 No Current salvage pT3 High 3.383984 TCC
GSM786579 DOD 69.1 Positive 51.5154 Yes male 1.0 T2 55.49867656 10 No Former adjuvant pT1 High 51.25257 TCC
GSM786580 NED 73.75 Positive 46.22587 No male nan T2 3.652001993 60 No Former adjuvant pT2 High 46.22587 TCC
GSM78658 NED 67.38 Negative 71.85216 No female 1.0 T4 78.0425585 not specified Yes Never not specified pT2 High 71.85216 TCC
GSM786582 DOD 64.83 Positive 5.716632 Yes male 2.0 T2 25.7632407 75 No Former not specified pT3 High 2.431211 TCC
GSM786583 NED 78.3 Nx 64.55852 No male 1.0 T2 64.19728557 30 No Former not specified pT2 High 64.55852 TCC

Tags

  • bladder cancer
  • cancer
  • carcinoma

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