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Home › Dataset Library › Expression data from human corneal endothelial cells

Dataset: Expression data from human corneal endothelial cells

Human corneal endothelial cells (HCEC) form a monolayer by adhering tightly through their intercellular adhesion molecules. Located at...

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Human corneal endothelial cells (HCEC) form a monolayer by adhering tightly through their intercellular adhesion molecules. Located at the posterior corneal surface, they maintain corneal translucency by dehydrating the corneal stroma, mainly through the Na+- and K+-dependent ATPase (Na+/K+-ATPase). Because HCEC proliferative activity is low in vivo,we tried to activate proliferation of HCEC by inhibiting cyclin-dependent kinase inhibitors.We have here demonstrated microarray data of transduced human corneal endothelial cell lines. Affymetrix human U133 plus 2.0 array was used to transcriptionally profile to compare cultured human corneal endothelial cells and transduced human corneal endothelial cells.

Species:
human

Samples:
3

Source:
E-GEOD-30781

Updated:
Dec.12, 2014

Registered:
Sep.16, 2014


Factors: (via ArrayExpress)
Sample GENOTYPE/VARIATION
GSM76365 transduced by Cdk4R24C/CyclinD1
GSM763652 transduced by human papillomavirus type E6/E7
GSM763653 non-transduced (primary)

Tags

  • cell
  • corneal endothelial cell
  • endothelial cell
  • posterior
  • stroma
  • surface

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