ArrayExpress Uploaderarrayexpress_sidhumancontrolcontrolcontrolCD28CD28CD3CD3CD3PMAPMAPMACD28, PMA, ControlCD28, PMA, ControlCD28, PMA, ControlCD28, CD3, ControlCD28, CD3, ControlCD28, CD3, ControlPMA, CD3, ControlPMA, CD3, ControlPMA, CD3, ControlCD28, PMA, A_420983CD28, PMA, A_420983CD28, PMA, CsACD28, PMA, CsACD28, PMA, AEB, 071CD28, PMA, AEB, 071CD28, PMA, Org48762CD28, PMA, Org48762CD28, PMA, SP600125CD28, PMA, SP600125CD28, PMA, PD98059CD28, PMA, PD98059CD28, CD3, A_420983CD28, CD3, A_420983CD28, CD3, CsACD28, CD3, CsACD28, CD3, AEB, 071CD28, CD3, AEB, 071CD28, CD3, Org48762CD28, CD3, Org48762CD28, CD3, SP600125CD28, CD3, SP600125CD28, CD3, PD98059CD28, CD3, PD98059PMA, CD3, A_420983PMA, CD3, A_420983PMA, CD3, CsAPMA, CD3, CsAPMA, CD3, AEB, 071PMA, CD3, AEB, 071PMA, CD3, Org48762PMA, CD3, Org48762PMA, CD3, SP600125PMA, CD3, SP600125PMA, CD3, PD98059PMA, CD3, PD98059417404T lymphocytes are orchestrators of adaptive immunity. Naïve T cells may differentiate into the Th1, Th2, Th17 or iTreg phenotype,...E-GEOD-30674/profile/8773/arrayexpressuploader156Dec.12, 2014Falseprofiling-of-jurkat-t-cells-activated-with-cd3-cd2E-GEOD-30674_A-AFFY-44Profiling of Jurkat T cells activated with CD3, CD28 and PMA and multiple kinase inhibitorsSep.16, 2014T lymphocytes are orchestrators of adaptive immunity. Naïve T cells may differentiate into the Th1, Th2, Th17 or iTreg phenotype, depending on environmental co-stimulatory signals. In order to identify the genes and pathways involved in differentiation of Jurkat T cells towards Th1 and Th2 subtypes we performed comprehensive transcriptome analyses of Jurkat T cells stimulated with various stimuli an pathway inhibitors Jurkat T cells were treated with CD3, CD28 and PMA and all pairwise combinations, in the presence of DMSO (control) or kinase inhibitors. RNA was isolated after 8 hrs incubation.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-30674http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-30674/samples/