4ArrayExpress Uploaderarrayexpress_sidhumancontrol0 hrcontrol1.5 hrscontrol3 hrscontrol4.5 hrshypoxia0 hrhypoxia1.5 hrshypoxia3 hrshypoxia4.5 hrstunicamycin0 hrtunicamycin1.5 hrstunicamycin3 hrstunicamycin4.5 hrsemetine0 hremetine1.5 hrsemetine3 hrsemetine4.5 hrsshRent10 hrshRent11.5 hrsshRent13 hrsshRent14.5 hrs41590http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-30499Nonsense-mediated RNA decay (NMD) is regulated by a variety of cellular stresses. We expose U2OS cells to several stresses and assess.../profile/8773/arrayexpressuploader220Dec.12, 2014Falseinhibition-of-nonsense-mediated-rna-decay-by-the-tE-GEOD-30499_A-AFFY-44Inhibition of nonsense-mediated RNA decay by the tumor microenvironment promotes tumorigenesisSep.16, 2014Nonsense-mediated RNA decay (NMD) is regulated by a variety of cellular stresses. We expose U2OS cells to several stresses and assess RNA expression in the absence of transcription (i.e. stability). These studies identify transcripts that are stabilized by the physiological inhibition of NMD. U2OS cells rendered hypoxia for three hours, treated with tunicamycin for three hours, treated with emetine for three hours, or depleted of Upf1/Rent1 were treated with DRB, and RNA was collected at 0, 1.5, 3 and 4.5 hrs.E-GEOD-30499http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-30499/samples/