ArrayExpress Uploader0mouseE2f3a-/-;E2f7-/-;E2f8-/-embryoE2f3a-/-;E2f7-/-;E2f8-/-embryoE2f3a-/-;E2f7-/-;E2f8-/-embryoE2f3a-/-;E2f7-/-;E2f8-/-embryoE2f3a-/-;E2f7-/-;E2f8-/-embryoE2f3a-/-;E2f7+/+;E2f8+/+embryoE2f3a-/-;E2f7+/+;E2f8+/+embryoE2f3a-/-;E2f7+/+;E2f8+/+embryoE2f3a-/-;E2f7+/+;E2f8+/+embryoE2f3a+/+;E2f7-/-;E2f8-/-embryoE2f3a+/+;E2f7-/-;E2f8-/-embryoE2f3a+/+;E2f7-/-;E2f8-/-embryoE2f3a+/+;E2f7-/-;E2f8-/-embryoCyp19Cre+;E2f7F/F;E2f8F/FembryoCyp19Cre+;E2f7F/F;E2f8F/FembryoCyp19Cre+;E2f7F/F;E2f8F/FembryoSox2Cre+;E2f7F/-;E2f8F/-embryoSox2Cre+;E2f7F/-;E2f8F/-embryoSox2Cre+;E2f7F/-;E2f8F/-embryoSox2Cre+;E2f7F/-;E2f8F/-embryoE2f3a+/+;E2f7+/+;E2f8+/+embryoE2f3a+/+;E2f7+/+;E2f8+/+embryoE2f3a+/+;E2f7+/+;E2f8+/+embryoE2f3a+/+;E2f7+/+;E2f8+/+embryoE2f3a+/+;E2f7+/+;E2f8+/+embryoE2f3a+/+;E2f7+/+;E2f8+/+embryoE2f3a-/-;E2f7-/-;E2f8-/-placentaE2f3a-/-;E2f7-/-;E2f8-/-placentaE2f3a-/-;E2f7-/-;E2f8-/-placentaE2f3a-/-;E2f7-/-;E2f8-/-placentaE2f3a-/-;E2f7-/-;E2f8-/-placentaE2f3a-/-;E2f7+/+;E2f8+/+placentaE2f3a-/-;E2f7+/+;E2f8+/+placentaE2f3a-/-;E2f7+/+;E2f8+/+placentaE2f3a-/-;E2f7+/+;E2f8+/+placentaE2f3a+/+;E2f7-/-;E2f8-/-placentaE2f3a+/+;E2f7-/-;E2f8-/-placentaE2f3a+/+;E2f7-/-;E2f8-/-placentaE2f3a+/+;E2f7-/-;E2f8-/-placentaCyp19Cre+;E2f7F/F;E2f8F/FplacentaCyp19Cre+;E2f7F/F;E2f8F/FplacentaCyp19Cre+;E2f7F/F;E2f8F/FplacentaSox2Cre+;E2f7F/-;E2f8F/-placentaSox2Cre+;E2f7F/-;E2f8F/-placentaSox2Cre+;E2f7F/-;E2f8F/-placentaSox2Cre+;E2f7F/-;E2f8F/-placentaE2f3a+/+;E2f7+/+;E2f8+/+placentaE2f3a+/+;E2f7+/+;E2f8+/+placentaE2f3a+/+;E2f7+/+;E2f8+/+placentaE2f3a+/+;E2f7+/+;E2f8+/+placentaE2f3a+/+;E2f7+/+;E2f8+/+placentaE2f3a+/+;E2f7+/+;E2f8+/+placenta6523arrayexpress_sid6To understand the underlying cause and mechanisms of embryonic lethality observed in combined loss of E2f7 and E2f8, we compared global...E-GEOD-30488/profile/8773/arrayexpressuploader252Dec.12, 2014Falseexpression-data-from-e2f7e2f8e2f3a-null-placentasE-GEOD-30488_A-AFFY-45Expression data from E2f7/E2f8/E2f3a null placentas and embryosNov.11, 2014To understand the underlying cause and mechanisms of embryonic lethality observed in combined loss of E2f7 and E2f8, we compared global gene expression profiles of wild type, germline deleted and sox2-Cre/Cyp19-Cre deleted embryos and placentas. RNA was extracted from E10.5 embryos and placentas. Gene deletion in samples confirmed by PCR genotyping of DNA isolated from each sample.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-30488http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-30488/samples/