{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSM75214": {"STATUS": "  ", "TISSUE TYPE": "cell line", "CELL TYPE": "astrocyte"}}, {"GSM75214": {"STATUS": "  ", "TISSUE TYPE": "cell line", "CELL TYPE": "astrocyte"}}, {"GSM75214": {"STATUS": "  ", "TISSUE TYPE": "cell line", "CELL TYPE": "astrocyte"}}, {"GSM75214": {"STATUS": "  ", "TISSUE TYPE": "cell line", "CELL TYPE": "astrocyte"}}, {"GSM75214": {"STATUS": "  ", "TISSUE TYPE": "cell line", "CELL TYPE": "astrocyte"}}, {"GSM75214": {"STATUS": "  ", "TISSUE TYPE": "cell line", "CELL TYPE": "astrocyte"}}], "id": 4150, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "Glioma CIMP (G-CIMP) is a powerful determinant of tumor pathogenicity but the molecular cause of G-CIMP is a fundamental question that is...", "geo_gse_id": "E-GEOD-30336", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 3, "sample_count": 6, "tags": ["cell", "glioma", "line"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "expression-analysis-of-52-glioma-clinical-samples", "geo_id_plat": "E-GEOD-30336_A-AFFY-44", "name": "Expression analysis of 52 glioma clinical samples (36 CIMP+ and 16 CIMP-) and 6 cell line samples", "created": "Sep.16, 2014", "summary": "Glioma CIMP (G-CIMP) is a powerful determinant of tumor pathogenicity but the molecular cause of G-CIMP is a fundamental question that is unresolved.  Here, we show that mutation of a single gene, isocitrate dehydrogenase 1 (IDH1), directly causes the G-CIMP in gliomas by remodeling the methylome. In this study 52 glioma clinic samples (36 CIMP+ and 16 CIMP-) were analyzed. Parental IDH1 wild-type and IDH1 mutant cells were passaged 40 and passage 40 were cell line was sent for expression array.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-30336", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-30336/samples/"}