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Home › Dataset Library › Neurod6 expression defines new retinal amacrine cell subtypes and regulates their fate

Dataset: Neurod6 expression defines new retinal amacrine cell subtypes and regulates their fate

The goal of this experiment was to define gene expression patterns of two mouse retinal neuron subsets that express the Thy1-mitoCFP-P...

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The goal of this experiment was to define gene expression patterns of two mouse retinal neuron subsets that express the Thy1-mitoCFP-P (MP) transgene. The two populations expressing the MP transgene are: 1) non-GABAergic, non-glycinergic amacrine cells; and 2) a subset of OFF-type bipolar cells. We used the VC1.1 monoclonal antibody, which labels amacrine cells (ACs) but not bipolar cells, to separately purify the AC and bipolar populations that express the MP transgene. Two biological replicates, originating from different litters, were collected for each sample. RNA was extracted from sorted cells and prepared for hybridization to Affymetrix microarrays.

Species:
mouse

Samples:
4

Source:
E-GEOD-30324

Updated:
Dec.12, 2014

Registered:
Nov.11, 2014


Factors: (via ArrayExpress)
Sample CELL TYPE
GSM751958 CFP+VC1.1+ retinal neurons
GSM751958 CFP+VC1.1+ retinal neurons
GSM751960 CFP+VC1.1– retinal neurons
GSM751960 CFP+VC1.1– retinal neurons

Tags

  • neuron

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