{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSM747366": {"DRUG": "5,\u00e2\u0080\u008b6-\u00e2\u0080\u008bdichloro-\u00e2\u0080\u008b1-\u00e2\u0080\u008b\u00ce\u00b2-\u00e2\u0080\u008bD-\u00e2\u0080\u008bribofuranosyl-\u00e2\u0080\u008b1H-\u00e2\u0080\u008bbenzimidazole"}}, {"GSM747366": {"DRUG": "5,\u00e2\u0080\u008b6-\u00e2\u0080\u008bdichloro-\u00e2\u0080\u008b1-\u00e2\u0080\u008b\u00ce\u00b2-\u00e2\u0080\u008bD-\u00e2\u0080\u008bribofuranosyl-\u00e2\u0080\u008b1H-\u00e2\u0080\u008bbenzimidazole"}}, {"GSM747366": {"DRUG": "5,\u00e2\u0080\u008b6-\u00e2\u0080\u008bdichloro-\u00e2\u0080\u008b1-\u00e2\u0080\u008b\u00ce\u00b2-\u00e2\u0080\u008bD-\u00e2\u0080\u008bribofuranosyl-\u00e2\u0080\u008b1H-\u00e2\u0080\u008bbenzimidazole"}}, {"GSM747363": {"DRUG": "Latrunculin B"}}, {"GSM747363": {"DRUG": "Latrunculin B"}}, {"GSM74736": {"DRUG": "N-[2-(4-chloroanilino)-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl) benz\u00ef\u00bf\u00bdamide"}}, {"GSM74736": {"DRUG": "N-[2-(4-chloroanilino)-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl) benz\u00ef\u00bf\u00bdamide"}}, {"GSM74736": {"DRUG": "N-[2-(4-chloroanilino)-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl) benz\u00ef\u00bf\u00bdamide"}}, {"GSM747366": {"DRUG": "5,\u00e2\u0080\u008b6-\u00e2\u0080\u008bdichloro-\u00e2\u0080\u008b1-\u00e2\u0080\u008b\u00ce\u00b2-\u00e2\u0080\u008bD-\u00e2\u0080\u008bribofuranosyl-\u00e2\u0080\u008b1H-\u00e2\u0080\u008bbenzimidazole"}}, {"GSM747366": {"DRUG": "5,\u00e2\u0080\u008b6-\u00e2\u0080\u008bdichloro-\u00e2\u0080\u008b1-\u00e2\u0080\u008b\u00ce\u00b2-\u00e2\u0080\u008bD-\u00e2\u0080\u008bribofuranosyl-\u00e2\u0080\u008b1H-\u00e2\u0080\u008bbenzimidazole"}}, {"GSM747366": {"DRUG": "5,\u00e2\u0080\u008b6-\u00e2\u0080\u008bdichloro-\u00e2\u0080\u008b1-\u00e2\u0080\u008b\u00ce\u00b2-\u00e2\u0080\u008bD-\u00e2\u0080\u008bribofuranosyl-\u00e2\u0080\u008b1H-\u00e2\u0080\u008bbenzimidazole"}}, {"GSM747363": {"DRUG": "Latrunculin B"}}, {"GSM747363": {"DRUG": "Latrunculin B"}}, {"GSM747363": {"DRUG": "Latrunculin B"}}, {"GSM74736": {"DRUG": "N-[2-(4-chloroanilino)-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl) benz\u00ef\u00bf\u00bdamide"}}, {"GSM74736": {"DRUG": "N-[2-(4-chloroanilino)-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl) benz\u00ef\u00bf\u00bdamide"}}, {"GSM74736": {"DRUG": "N-[2-(4-chloroanilino)-1-methyl-2-oxoethoxy]-3,5-bis(trifluoromethyl) benz\u00ef\u00bf\u00bdamide"}}, {"GSM747349": {"DRUG": "DMSO control"}}, {"GSM747349": {"DRUG": "DMSO control"}}, {"GSM747349": {"DRUG": "DMSO control"}}], "id": 2453, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "Analysis of serum starved PC-3 cells treated with CCG-1423, Latrunculin B, or the transcription elongation inhibitor DRB for 2 or 24...", "geo_gse_id": "E-GEOD-30188", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 20, "tags": ["actin", "cancer", "serum"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "rho-transcription-inhibitor-ccg-1423-effect-on-pc", "geo_id_plat": "E-GEOD-30188_A-AFFY-44", "name": "Rho transcription inhibitor CCG-1423 effect on PC-3 cells", "created": "Jul.12, 2014", "summary": "Analysis of serum starved PC-3 cells treated with CCG-1423, Latrunculin B, or the transcription elongation inhibitor DRB for 2 or 24 hours. Results provide insights to potential therapeutic approaches to cancer metastasis. Twenty one samples in triplicate were analyzed and compared to the DMSO-treated control. The primary condition tested was the effect of the Rho-transcription pathway inhibitor, CCG-1423 As a biologically related control, the actin polymerization inhibitor, Latrunculin B, that also blocks Rho-stimulated gene transcription was tested. As a control for non-specific transcription inhibition, DRB was used. All samples, 2-hr and 24-hr treated samples were compared to the 24-hr DMSO sample.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-30188", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-30188/samples/"}