{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSM746726": {"DISEASE STATE": "Systemic lupus erythematosous (SLE)", "INDIVIDUAL": "patient1"}}, {"GSM746727": {"DISEASE STATE": "Systemic lupus erythematosous (SLE)", "INDIVIDUAL": "patient2"}}, {"GSM746728": {"DISEASE STATE": "Systemic lupus erythematosous (SLE)", "INDIVIDUAL": "patient3"}}, {"GSM746729": {"DISEASE STATE": "Systemic lupus erythematosous (SLE)", "INDIVIDUAL": "patient4"}}, {"GSM746730": {"DISEASE STATE": "Systemic lupus erythematosous (SLE)", "INDIVIDUAL": "patient5"}}, {"GSM74673": {"DISEASE STATE": "Systemic lupus erythematosous (SLE)", "INDIVIDUAL": "patient6"}}, {"GSM746732": {"DISEASE STATE": "Systemic lupus erythematosous (SLE)", "INDIVIDUAL": "patient7"}}, {"GSM746733": {"DISEASE STATE": "Systemic lupus erythematosous (SLE)", "INDIVIDUAL": "patient8"}}, {"GSM746734": {"DISEASE STATE": "Systemic lupus erythematosous (SLE)", "INDIVIDUAL": "patient9"}}, {"GSM746735": {"DISEASE STATE": "Systemic lupus erythematosous (SLE)", "INDIVIDUAL": "patient10"}}, {"GSM746736": {"DISEASE STATE": "Systemic lupus erythematosous (SLE)", "INDIVIDUAL": "patient11"}}, {"GSM746737": {"DISEASE STATE": "Systemic lupus erythematosous (SLE)", "INDIVIDUAL": "patient12"}}, {"GSM746738": {"DISEASE STATE": "Systemic lupus erythematosous (SLE)", "INDIVIDUAL": "patient13"}}, {"GSM746739": {"DISEASE STATE": "Systemic lupus erythematosous (SLE)", "INDIVIDUAL": "patient14"}}, {"GSM746740": {"DISEASE STATE": "Systemic lupus erythematosous (SLE)", "INDIVIDUAL": "patient15"}}, {"GSM74674": {"DISEASE STATE": "Systemic lupus erythematosous (SLE)", "INDIVIDUAL": "patient16"}}, {"GSM746742": {"DISEASE STATE": "Systemic lupus erythematosous (SLE)", "INDIVIDUAL": "patient17"}}, {"GSM746743": {"DISEASE STATE": "control", "INDIVIDUAL": "Control1"}}, {"GSM746744": {"DISEASE STATE": "control", "INDIVIDUAL": "Control2"}}, {"GSM746745": {"DISEASE STATE": "control", "INDIVIDUAL": "Control3"}}, {"GSM746746": {"DISEASE STATE": "control", "INDIVIDUAL": "Control4"}}, {"GSM746747": {"DISEASE STATE": "control", "INDIVIDUAL": "Control5"}}, {"GSM746748": {"DISEASE STATE": "control", "INDIVIDUAL": "Control6"}}, {"GSM746750": {"DISEASE STATE": "control", "INDIVIDUAL": "Control8"}}, {"GSM74675": {"DISEASE STATE": "control", "INDIVIDUAL": "Control9"}}, {"GSM746752": {"DISEASE STATE": "control", "INDIVIDUAL": "Control10"}}], "id": 4141, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "Systemic lupus erythematosous (SLE) is an autoimmune disease with an important clinical and biological heterogeneity. B lymphocytes...", "geo_gse_id": "E-GEOD-30153", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 26, "tags": ["autoimmune disease", "cell", "central", "disease", "hypergammaglobulinemia", "lupus", "peripheral"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_id_plat": "E-GEOD-30153_A-AFFY-44", "slug": "b-cell-signature-during-inactive-systemic-lupus", "geo_gds_id": "", "name": "B cell signature during inactive systemic lupus", "created": "Sep.16, 2014", "summary": "Systemic lupus erythematosous (SLE) is an autoimmune disease with an important clinical and biological heterogeneity. B lymphocytes appear central to the development of SLE which is characterized by the production of a large variety of autoantibodies and hypergammaglobulinemia. In mice, immature B cells from spontaneous lupus prone animals are able to produce autoantibodies when transferred into immunodeficient mice, strongly suggesting the existence of intrinsic B cell defects during lupus. In order to approach these defects in humans, we compared the peripheral B cell transcriptomes of quiescent lupus patients to normal B cell transcriptomes. 17 patients with quiescent lupus (patient1-17) versus 9 controls (Control1-6,Control8-10).", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-30153", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-30153/samples/"}