{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSM742112": {"ORGANISM PART": "nodal tumor", "DIAGNOSIS": "lymphoblastic tumor biopsy"}}, {"GSM742112": {"ORGANISM PART": "nodal tumor", "DIAGNOSIS": "lymphoblastic tumor biopsy"}}, {"GSM742112": {"ORGANISM PART": "nodal tumor", "DIAGNOSIS": "lymphoblastic tumor biopsy"}}, {"GSM742112": {"ORGANISM PART": "nodal tumor", "DIAGNOSIS": "lymphoblastic tumor biopsy"}}, {"GSM742112": {"ORGANISM PART": "nodal tumor", "DIAGNOSIS": "lymphoblastic tumor biopsy"}}, {"GSM742112": {"ORGANISM PART": "nodal tumor", "DIAGNOSIS": "lymphoblastic tumor biopsy"}}, {"GSM742112": {"ORGANISM PART": "nodal tumor", "DIAGNOSIS": "lymphoblastic tumor biopsy"}}, {"GSM742112": {"ORGANISM PART": "nodal tumor", "DIAGNOSIS": "lymphoblastic tumor biopsy"}}, {"GSM742112": {"ORGANISM PART": "nodal tumor", "DIAGNOSIS": "lymphoblastic tumor biopsy"}}, {"GSM742112": {"ORGANISM PART": "nodal tumor", "DIAGNOSIS": "lymphoblastic tumor biopsy"}}, {"GSM742112": {"ORGANISM PART": "nodal tumor", "DIAGNOSIS": "lymphoblastic tumor biopsy"}}, {"GSM742112": {"ORGANISM PART": "nodal tumor", "DIAGNOSIS": "lymphoblastic tumor biopsy"}}, {"GSM742112": {"ORGANISM PART": "nodal tumor", "DIAGNOSIS": "lymphoblastic tumor biopsy"}}, {"GSM742112": {"ORGANISM PART": "nodal tumor", "DIAGNOSIS": "lymphoblastic tumor biopsy"}}, {"GSM742112": {"ORGANISM PART": "nodal tumor", "DIAGNOSIS": "lymphoblastic tumor biopsy"}}, {"GSM742112": {"ORGANISM PART": "nodal tumor", "DIAGNOSIS": "lymphoblastic tumor biopsy"}}, {"GSM742112": {"ORGANISM PART": "nodal tumor", "DIAGNOSIS": "lymphoblastic tumor biopsy"}}, {"GSM742112": {"ORGANISM PART": "nodal tumor", "DIAGNOSIS": "lymphoblastic tumor biopsy"}}, {"GSM742112": {"ORGANISM PART": "nodal tumor", "DIAGNOSIS": "lymphoblastic tumor biopsy"}}, {"GSM742112": {"ORGANISM PART": "nodal tumor", "DIAGNOSIS": "lymphoblastic tumor biopsy"}}, {"GSM742132": {"ORGANISM PART": "bone marrow", "DIAGNOSIS": "T-cell acute lymphoblastic leukemia bone marrow"}}, {"GSM742132": {"ORGANISM PART": "bone marrow", "DIAGNOSIS": "T-cell acute lymphoblastic leukemia bone marrow"}}, {"GSM742132": {"ORGANISM PART": "bone marrow", "DIAGNOSIS": "T-cell acute lymphoblastic leukemia bone marrow"}}, {"GSM742132": {"ORGANISM PART": "bone marrow", "DIAGNOSIS": "T-cell acute lymphoblastic leukemia bone marrow"}}, {"GSM742132": {"ORGANISM PART": "bone marrow", "DIAGNOSIS": "T-cell acute lymphoblastic leukemia bone marrow"}}, {"GSM742132": {"ORGANISM PART": "bone marrow", "DIAGNOSIS": "T-cell acute lymphoblastic leukemia bone marrow"}}, {"GSM742132": {"ORGANISM PART": "bone marrow", "DIAGNOSIS": "T-cell acute lymphoblastic leukemia bone marrow"}}, {"GSM742132": {"ORGANISM PART": "bone marrow", "DIAGNOSIS": "T-cell acute lymphoblastic leukemia bone marrow"}}, {"GSM742132": {"ORGANISM PART": "bone marrow", "DIAGNOSIS": "T-cell acute lymphoblastic leukemia bone marrow"}}, {"GSM742132": {"ORGANISM PART": "bone marrow", "DIAGNOSIS": "T-cell acute lymphoblastic leukemia bone marrow"}}, {"GSM742142": {"ORGANISM PART": "bone marrow", "DIAGNOSIS": "common  lymphoblastic leukemia bone marrow"}}, {"GSM742142": {"ORGANISM PART": "bone marrow", "DIAGNOSIS": "common  lymphoblastic leukemia bone marrow"}}, {"GSM742142": {"ORGANISM PART": "bone marrow", "DIAGNOSIS": "common  lymphoblastic leukemia bone marrow"}}, {"GSM742142": {"ORGANISM PART": "bone marrow", "DIAGNOSIS": "common  lymphoblastic leukemia bone marrow"}}, {"GSM742142": {"ORGANISM PART": "bone marrow", "DIAGNOSIS": "common  lymphoblastic leukemia bone marrow"}}, {"GSM742142": {"ORGANISM PART": "bone marrow", "DIAGNOSIS": "common  lymphoblastic leukemia bone marrow"}}], "id": 4138, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "T-cell acute lymphoblastic leukemia (T-ALL) and lymphoma (T-LBL) share common morphologic and immunophenotypic features and are treated...", "geo_gse_id": "E-GEOD-29986", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 36, "tags": ["acute lymphoblastic leukemia", "bone", "bone marrow", "cell", "genome", "leukemia", "lymphoblastic leukemia", "lymphoma"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "gene-expression-analyses-of-pediatric-lymphoblasti", "geo_id_plat": "E-GEOD-29986_A-AFFY-44", "name": "gene expression analyses of pediatric  lymphoblastic lymphomas and leukemias", "created": "Sep.16, 2014", "summary": "T-cell acute lymphoblastic leukemia (T-ALL) and lymphoma (T-LBL) share common morphologic and immunophenotypic features and are treated with similar therapeutic approaches. Nonetheless, they show distinct clinical presentations suggesting that they may represent two different biological entities. In order to investigate T-LBL and T-ALL biological characteristics we used  transcriptional profiling approache. Genome-wide gene expression profiling, performed on 20 T-LBL and 10 T-ALL diagnostic specimens, showed that the two malignancies shared a large fraction of their transcriptional profile while a subset of genes appeared to be differentially expressed in T-LBL versus T-ALL. This gene signature included genes involved in chemotactic responses and angiogenesis which might play a role in the different tumor cell localization suggesting that T-LBL and T-ALL could be  two distinct diseases with unique transcriptional  characteristics. diagnostic bone marrow  aspirates from 10 T-ALL and 6 common-ALL pediatric patients and  tumor biopsies from 20 T-LBL  pediatric patients were analyzed by gene expression profiling", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-29986", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-29986/samples/"}