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<biogps><data><item key="owner">ArrayExpress Uploader</item><item key="ownerprofile_id">arrayexpress_sid</item><item key="species">human</item><item key="factors"><item><item key="GSM734352"><item key="VARIATION">control</item></item></item><item><item key="GSM734353"><item key="VARIATION">galectin-3 silenced</item></item></item></item><item key="id">4111</item><item key="pop_total">0</item><item key="platform">4</item><item key="summary_wrapped">Although galectin-3 is known to modulate the cell proliferation, RNA processing, tumorigenesis, metastasis and apoptosis and also, which...</item><item key="owner_profile">/profile/8773/arrayexpressuploader</item><item key="factor_count">1</item><item key="sample_count">2</item><item key="tags"><item>cancer</item><item>cell</item></item><item key="lastmodified">Dec.12, 2014</item><item key="is_default">False</item><item key="geo_id_plat">E-GEOD-29630_A-AFFY-44</item><item key="slug">galectin-3-regulates-the-expression-of-various-gen</item><item key="source">http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-29630</item><item key="geo_gds_id"/><item key="name">Galectin-3 regulates the expression of various genes in human gastric cancer cells</item><item key="created">Sep.16, 2014</item><item key="summary">Although galectin-3 is known to modulate the cell proliferation, RNA processing, tumorigenesis, metastasis and apoptosis and also, which is highly expressed in human cancers, the function of galectin-3 is still controversy in gastric cancer. Here, we demonstrated the function of galectin-3 on gastric cancers by silencing with synthetic double-stranded small interfering RNA (siRNA). After silencing of galectin-3, cell numbers decreased and cell shapes changed in round. To determine the mechanism, microarray analysis was used to detect the changes in gene expression by galectin-3 silencing. we silenced galectin-3 in AGS as a gastric cancer cells with synthetic double-stranded small interfering RNA (siRNA), and performed the microarray analysis to detect the changes in gene expression by galectin-3 silencing.</item><item key="geo_gse_id">E-GEOD-29630</item><item key="sample_source">http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-29630/samples/</item></data></biogps>
