{"owner": "ArrayExpress Uploader", "ownerprofile_id": "arrayexpress_sid", "species": "human", "factors": [{"GSM734352": {"VARIATION": "control"}}, {"GSM734353": {"VARIATION": "galectin-3 silenced"}}], "id": 4111, "pop_total": 0, "platform": 4, "summary_wrapped": "Although galectin-3 is known to modulate the cell proliferation, RNA processing, tumorigenesis, metastasis and apoptosis and also, which...", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 2, "tags": ["cancer", "cell"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_id_plat": "E-GEOD-29630_A-AFFY-44", "slug": "galectin-3-regulates-the-expression-of-various-gen", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-29630", "geo_gds_id": "", "name": "Galectin-3 regulates the expression of various genes in human gastric cancer cells", "created": "Sep.16, 2014", "summary": "Although galectin-3 is known to modulate the cell proliferation, RNA processing, tumorigenesis, metastasis and apoptosis and also, which is highly expressed in human cancers, the function of galectin-3 is still controversy in gastric cancer. Here, we demonstrated the function of galectin-3 on gastric cancers by silencing with synthetic double-stranded small interfering RNA (siRNA). After silencing of galectin-3, cell numbers decreased and cell shapes changed in round. To determine the mechanism, microarray analysis was used to detect the changes in gene expression by galectin-3 silencing. we silenced galectin-3 in AGS as a gastric cancer cells with synthetic double-stranded small interfering RNA (siRNA), and performed the microarray analysis to detect the changes in gene expression by galectin-3 silencing.", "geo_gse_id": "E-GEOD-29630", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-29630/samples/"}