Dataset: Expression data from Notch-activated CD34+CD45RA-Lin- hematopoietic progenitor cells (HPCs) transduced with nuclear-trapped AF1q/MLLT11 (A2M)
We used microarrays to examine the impact of AF1q/MLLT11 on the gene expression profile of Notch-activated CD34+CD45RA-Lin- HPCs isolated...
We used microarrays to examine the impact of AF1q/MLLT11 on the gene expression profile of Notch-activated CD34+CD45RA-Lin- HPCs isolated from umbilical cord blood CD34+CD45RA-Lin- HPCs correspond to early multipotent progenitors. A2M is a nuclear mutant derivative of AF1q/MLLT11 CD34+CD45RA-Lin- HPCs were FACS-sorted, exposed to A2M or control vectors, sorted again based on GFP expression, and cultured for 72 hrs with graded doses of plastic-immobilized Notch ligand Delta1ext-IgG
- Species:
- human
- Samples:
- 6
- Source:
- E-GEOD-29524
- Updated:
- Dec.12, 2014
- Registered:
- Sep.16, 2014
Factors:
(via ArrayExpress)
| Sample | TREATMENT GROUP | VARIATION |
|---|---|---|
| GSM73068 | control | transduced with empty vector |
| GSM730682 | control | transduced with A2M |
| GSM730683 | Notch-activated (2 �g) | transduced with empty vector |
| GSM730684 | Notch-activated (2 �g) | transduced with A2M |
| GSM730685 | Notch-activated (5 �g) | transduced with empty vector |
| GSM730686 | Notch-activated (5 �g) | transduced with A2M |