8ArrayExpress Uploader0mouse8554arrayexpress_sidhttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-29426Mouse FGF15 and human FGF19 are orthologous proteins that regulate bile acid metabolism. However, other hepatic functions of FGF15/19.../profile/8773/arrayexpressuploader06genomeliquidliverveinDec.12, 2014Falseeffect-of-fgf15-or-fgf19-on-mouse-liverE-GEOD-29426_A-AFFY-36Effect of FGF15 or FGF19 on mouse liverNov.24, 2014Mouse FGF15 and human FGF19 are orthologous proteins that regulate bile acid metabolism. However, other hepatic functions of FGF15/19 are not well characterized. We used microarrays to analyze global hepatic gene expression in mice administered FGF15 or FGF19. Total liver RNA was isolated from wild-type mice administered vehicle, purified FGF15 or recombinant FGF19 for 6 hr via a jugular vein injection as described (Inagaki et al., 2005). Mice did not have access to food throughout the 6 hr treatment, and livers were harvested and immediately frozen in liquid nitrogen. Microarray analyses were performed using the Mouse Genome 430A 2.0 array.E-GEOD-29426http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-29426/samples/