{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSM720404": {"TREATMENT": "none"}}, {"GSM720404": {"TREATMENT": "none"}}, {"GSM720404": {"TREATMENT": "none"}}, {"GSM720404": {"TREATMENT": "none"}}, {"GSM720404": {"TREATMENT": "none"}}, {"GSM720404": {"TREATMENT": "none"}}, {"GSM720404": {"TREATMENT": "none"}}, {"GSM720404": {"TREATMENT": "none"}}, {"GSM720404": {"TREATMENT": "none"}}, {"GSM720413": {"TREATMENT": "zebularine"}}, {"GSM720413": {"TREATMENT": "zebularine"}}, {"GSM720413": {"TREATMENT": "zebularine"}}, {"GSM720413": {"TREATMENT": "zebularine"}}, {"GSM720413": {"TREATMENT": "zebularine"}}, {"GSM720413": {"TREATMENT": "zebularine"}}, {"GSM720413": {"TREATMENT": "zebularine"}}, {"GSM720413": {"TREATMENT": "zebularine"}}, {"GSM720413": {"TREATMENT": "zebularine"}}], "id": 6460, "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "Lineage commitment during Embryonic Stem Cells (ESCs) differentiation is controlled not only by a gamut of transcription factors but also...", "geo_gse_id": "E-GEOD-29072", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 18, "tags": ["cell", "cytosine", "histone", "stem cell"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_id_plat": "E-GEOD-29072_A-AFFY-45", "slug": "zebularine-effect-on-mouse-embryonic-stem-cells-ma", "geo_gds_id": "", "name": "Zebularine effect on mouse embryonic stem cells manifested as cardiod-myogenic potential: testable hypothesis generation using microarray data", "created": "Nov.11, 2014", "summary": "Lineage commitment during Embryonic Stem Cells (ESCs) differentiation is controlled not only by a gamut of transcription factors but also by epigenetic events, mainly histone deacetylation and promoter DNA methylation. Moreover, the DNA demethylation agent 5\u2032-Aza-2\u2032-deoxycytidine (AzadC) has been widely described in the literature as an effective chemical stimulus used to promote cardiomyogenic differentiation in various stem cell types; however, its toxicity and instability complicate its use. Thus, the purpose of this study was to examine the effects of zebularine, a stable and non-toxic DNA cytosine methylation inhibitor, on ESCs differentiation. Herein are the Affymetrix Expression data obtained from RNA of murine ESCs treated with zebularine. 9 control samples (replicates) and 9 zebularine samples (replicates).", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-29072", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-29072/samples/"}