{"owner": "ArrayExpress Uploader", "ownerprofile_id": "arrayexpress_sid", "id": 4046, "factors": [{"GSM707672": {"SIRNA": "control", "TREATMENT": "none", "TREATMENT DURATION": "not specified"}}, {"GSM707673": {"SIRNA": "control", "TREATMENT": "TGF-beta", "TREATMENT DURATION": "1.5 hrs"}}, {"GSM707674": {"SIRNA": "control", "TREATMENT": "TGF-beta", "TREATMENT DURATION": "24 hrs"}}, {"GSM707675": {"SIRNA": "HNF4a", "TREATMENT": "none", "TREATMENT DURATION": "not specified"}}, {"GSM707676": {"SIRNA": "HNF4a", "TREATMENT": "TGF-beta", "TREATMENT DURATION": "1.5 hrs"}}, {"GSM707677": {"SIRNA": "HNF4a", "TREATMENT": "TGF-beta", "TREATMENT DURATION": "24 hrs"}}], "pop_total": 0, "platform": 4, "summary_wrapped": "Smad2/3 are transcription factors that engage in TGF-beta-induced transcription. We determined and analyzed HepG2 and Hep3B-specific...", "pubmed_id": 21646355, "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 3, "sample_count": 6, "tags": [], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_id_plat": "E-GEOD-28590_A-AFFY-44", "slug": "expression-data-of-the-human-hepatoblastoma-cell-l", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-28590", "geo_gds_id": "", "name": "Expression data of the human hepatoblastoma cell line HepG2 treated with TGF-beta", "created": "Sep.16, 2014", "summary": "Smad2/3 are transcription factors that engage in TGF-beta-induced transcription. We determined and analyzed HepG2 and Hep3B-specific Smad2/3 binding sites by ChIP-chip. We used expression microarrays to compare the Smad2/3 and HNF4alpha binding sites identified by ChIP-chip or ChIP-seq, respectively, to TGF-beta-induced gene expressions. HepG2 cells were transfected with control or HNF4A siRNAs and treated with 3 ng/ml TGF-beta for 0, 1.5 and 24 h (6 samples in total, no replicates). Total RNA was extracted and expression microarray analysis was performed as described in the protocols.", "geo_gse_id": "E-GEOD-28590", "species": "human", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-28590/samples/"}