{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSM707024 1": {}}, {"GSM707025 1": {}}, {"GSM707026 1": {}}, {"GSM707027 1": {}}, {"GSM707028 1": {}}, {"GSM707029 1": {}}, {"GSM707030 1": {}}, {"GSM707031 1": {}}, {"GSM707032 1": {}}, {"GSM707033 1": {}}, {"GSM707034 1": {}}, {"GSM707035 1": {}}, {"GSM707036 1": {}}, {"GSM707037 1": {}}, {"GSM707038 1": {}}, {"GSM707039 1": {}}, {"GSM707040 1": {}}, {"GSM707041 1": {}}, {"GSM707042 1": {}}, {"GSM707043 1": {}}, {"GSM707044 1": {}}, {"GSM707045 1": {}}, {"GSM707046 1": {}}, {"GSM707047 1": {}}], "id": 4044, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "SIRT6 has been implicated in a range of biological processes including inflammation, aging and the control of metabolism. Hence...", "geo_gse_id": "E-GEOD-28548", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 0, "sample_count": 24, "tags": ["genome"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "the-effect-of-sirtuin-6-overexpression-on-tnfa-sti", "geo_id_plat": "E-GEOD-28548_A-AFFY-44", "name": "The effect of sirtuin 6 overexpression on TNFa stimulation.", "created": "Sep.16, 2014", "summary": "SIRT6 has been implicated in a range of biological processes including inflammation, aging and the control of metabolism. Hence inhibitors or activators of SIRT6 have the potential to be therapeutics for a number of indications. Genome wide expression studies were used to investigate the effect of overexpression of SIRT6 and mutant SIRT6 on a wide range of NF\u03baB dependent gene expression HEK293 cells were transfected with expression vectors encoding wild type SIRT6 or the H133W mutant followed by stimulation with TNF\u03b1 for one hour.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-28548", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-28548/samples/"}