{"owner": "ArrayExpress Uploader", "pop_total": 0, "id": 4037, "factors": [{"GSM703788": {"TUMOR SECRETION PROFILE": "None", "GENOTYPE": "WT CTNNB1", "ORGANISM PART": "Normal adrenal glands"}}, {"GSM703789": {"TUMOR SECRETION PROFILE": "cortisol", "GENOTYPE": "CTNNB1 mutation (S45P)", "ORGANISM PART": "adrenocortical adenoma"}}, {"GSM703790": {"TUMOR SECRETION PROFILE": "aldosterone", "GENOTYPE": "CTNNB1 mutation (T41A)", "ORGANISM PART": "adrenocortical adenoma"}}, {"GSM70379": {"TUMOR SECRETION PROFILE": "cortisol", "GENOTYPE": "CTNNB1 mutation (S37C)", "ORGANISM PART": "adrenocortical adenoma"}}, {"GSM703792": {"TUMOR SECRETION PROFILE": "cortisol", "GENOTYPE": "WT CTNNB1", "ORGANISM PART": "adrenocortical adenoma"}}, {"GSM703792": {"TUMOR SECRETION PROFILE": "cortisol", "GENOTYPE": "WT CTNNB1", "ORGANISM PART": "adrenocortical adenoma"}}, {"GSM703792": {"TUMOR SECRETION PROFILE": "cortisol", "GENOTYPE": "WT CTNNB1", "ORGANISM PART": "adrenocortical adenoma"}}, {"GSM703795": {"TUMOR SECRETION PROFILE": "aldosterone", "GENOTYPE": "WT CTNNB1", "ORGANISM PART": "adrenocortical adenoma"}}], "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "Mutations of \u03b2-catenin gene (CTNNB1) are frequent in adrenocortical adenomas (AA) and carcinomas (ACC). However, the target genes of...", "pubmed_id": 21565795, "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 3, "sample_count": 8, "tags": ["adenomas"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_id_plat": "E-GEOD-28476_A-AFFY-44", "slug": "characterization-of-differential-gene-expression-i", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-28476", "geo_gds_id": "", "name": "Characterization of differential gene expression in adrenocortical tumors harbouring \u03b2-catenin  (CTNNB1) mutations.", "created": "Sep.16, 2014", "summary": "Mutations of \u03b2-catenin gene (CTNNB1) are frequent in adrenocortical adenomas (AA) and carcinomas (ACC). However, the target genes of CTNNB1 have not yet been identified in adrenocortical tumors. Our objective was to identify genes de-regulated in adrenocortical tumors harbouring CTNNB1 genetic alterations. We compared gene expression profiles of AA with (n: 3) and without (n: 4) CTNNB1 mutations using Affymetrix arrays.", "geo_gse_id": "E-GEOD-28476", "species": "human", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-28476/samples/"}