ArrayExpress Uploader06428Bcl11a +/+wildtypeBcl11a +/+wildtypeBcl11a +/+wildtypeBcl11a fl/fl EpoR-Cre+BCL11A knockoutBcl11a fl/fl EpoR-Cre+BCL11A knockoutBcl11a fl/fl EpoR-Cre+BCL11A knockoutarrayexpress_sid6BCL11A is a critical mediator of hemoglobin switching and gamma-globin silencing. In this study, we showed the BCL11A is required in vivo...21998251/profile/8773/arrayexpressuploader26bonehemoglobinDec.12, 2014FalseE-GEOD-28333_A-AFFY-45expression-data-from-bcl11a-null-and-wild-type-bonhttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-28333Expression data from BCL11A-null and wild-type bone marrow erythroid pregenitorsNov.11, 2014BCL11A is a critical mediator of hemoglobin switching and gamma-globin silencing. In this study, we showed the BCL11A is required in vivo for developmental silencing of gamma-globin genes in adult animals. We used microarray to determine the changes in gene expression profile after loss of BCL11A in adult erythroid cells CD71+Ter119+ erythroid progenitor cells were FACS-sorted from bone marrows of 6-week old control (Bcl11a +/+) and BCL11A knockout (Bcl11a fl/fl EpoR-Cre+) mice.E-GEOD-28333mousehttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-28333/samples/