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Home › Dataset Library › Gene expression data from human CD34+ cord blood cells infected with MIGR1, MIGR1-AML1-ETO or MIGR1-AML1-ETO∆NHR1

Dataset: Gene expression data from human CD34+ cord blood cells infected with MIGR1, MIGR1-AML1-ETO or MIGR1-AML1-ETO∆NHR1

Compare the gene expression profile among human CD34+ cord blood cells infected with MIGR1, MIGR1-AML1-ETO or MIGR1-AML1-ETO∆NHR1...

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Compare the gene expression profile among human CD34+ cord blood cells infected with MIGR1, MIGR1-AML1-ETO or MIGR1-AML1-ETO∆NHR1 AML1-ETO promotes the self-renewal of human hematopoietic stem/progenitor cells (HSPCs). We found deletion of NHR1 domain abrogates AML1-ETO induced expasion of HSPCs. GFP+CD34+ human cord blood cells were sorted by FACS 72 hours after the infection for RNA extraction and hybridyzation for Affymetrix microarrays.

Species:
human

Samples:
9

Source:
E-GEOD-28317

PubMed:
21764752

Updated:
Dec.12, 2014

Registered:
Sep.16, 2014


Factors: (via ArrayExpress)
Sample INFECTION
GSM700450 MIGR1-AML1-ETO
GSM700450 MIGR1-AML1-ETO
GSM700450 MIGR1-AML1-ETO
GSM700453 MIGR1-AML1-ETO∆NHR1
GSM700453 MIGR1-AML1-ETO∆NHR1
GSM700453 MIGR1-AML1-ETO∆NHR1
GSM700456 MIGR1
GSM700456 MIGR1
GSM700456 MIGR1

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