ArrayExpress Uploader03984empty vector (pCDNA3.1)empty vector (pCDNA3.1)pcDNA3.1-PRDM1αpcDNA3.1-PRDM1αpcDNA3.1-LMP1pcDNA3.1-LMP1arrayexpress_sid4In this study, we have investigated the effect of BLIMP1α on gene expression, cell differentiation and pathogenesis in normal human GC B...21411757E-GEOD-27670/profile/8773/arrayexpressuploader16cellDec.12, 2014Falsedown-regulation-of-blimp1-alpha-by-the-ebv-oncogenE-GEOD-27670_A-AFFY-44Down-regulation of BLIMP1-alpha by the EBV oncogene, LMP1, disrupts the plasma cell differentiation program and prevents viral replication in B cellsSep.15, 2014In this study, we have investigated the effect of BLIMP1α on gene expression, cell differentiation and pathogenesis in normal human GC B cells using a non-viral vector based system Gene expression was compared among BLIMP1α, LMP1-transfected and control vector-transfected GC B cells from two patients. RNA from the FACS-sorted transfected GC B cells was amplified. Fragmented cRNA was hybridized to HG-U133 Plus 2.0 microarrays. Differentially expressed genes were identified using the GCOS pair-wise analysis.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-27670humanhttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-27670/samples/