{"owner": "ArrayExpress Uploader", "pop_total": 0, "id": 3984, "factors": [{"GSM685339": {"TRANSFECTION": "empty vector (pCDNA3.1)"}}, {"GSM685339": {"TRANSFECTION": "empty vector (pCDNA3.1)"}}, {"GSM685345": {"TRANSFECTION": "pcDNA3.1-PRDM1\u03b1"}}, {"GSM685345": {"TRANSFECTION": "pcDNA3.1-PRDM1\u03b1"}}, {"GSM685379": {"TRANSFECTION": "pcDNA3.1-LMP1"}}, {"GSM685379": {"TRANSFECTION": "pcDNA3.1-LMP1"}}], "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "In this study, we have investigated the effect of BLIMP1\u03b1 on gene expression, cell differentiation and pathogenesis in normal human GC B...", "pubmed_id": 21411757, "geo_gse_id": "E-GEOD-27670", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 6, "tags": ["cell"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "down-regulation-of-blimp1-alpha-by-the-ebv-oncogen", "geo_id_plat": "E-GEOD-27670_A-AFFY-44", "name": "Down-regulation of BLIMP1-alpha by the EBV oncogene, LMP1, disrupts the plasma cell differentiation program and prevents viral replication in B cells", "created": "Sep.15, 2014", "summary": "In this study, we have investigated the effect of BLIMP1\u03b1 on gene expression, cell differentiation and pathogenesis in normal human GC B cells using a non-viral vector based system Gene expression was compared among BLIMP1\u03b1, LMP1-transfected and control vector-transfected GC B cells from two patients. RNA from the FACS-sorted transfected GC B cells was amplified. Fragmented cRNA was hybridized to HG-U133 Plus 2.0 microarrays. Differentially expressed genes were identified using the GCOS pair-wise analysis.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-27670", "species": "human", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-27670/samples/"}