ArrayExpress Uploaderarrayexpress_sidhumanSotos syndrome with NSD1 abnormalityRETINOIC ACIDSotos syndrome with NSD1 abnormalityuntreatedSotos syndrome with NSD1 abnormalityRETINOIC ACIDSotos syndrome with NSD1 abnormalityuntreatedSotos syndrome with NSD1 abnormalityRETINOIC ACIDSotos syndrome with NSD1 abnormalityuntreatedSotos syndrome with NSD1 abnormalityRETINOIC ACIDSotos syndrome with NSD1 abnormalityuntreatedSotos syndrome with NSD1 abnormalityRETINOIC ACIDSotos syndrome with NSD1 abnormalityuntreatedSotos syndrome with NSD1 abnormalityRETINOIC ACIDSotos syndrome with NSD1 abnormalityuntreatedSotos syndrome with NSD1 abnormalityRETINOIC ACIDSotos syndrome with NSD1 abnormalityuntreatedSotos syndrome with NSD1 abnormalityRETINOIC ACIDSotos syndrome with NSD1 abnormalityuntreatedSotos syndrome with NSD1 abnormalityRETINOIC ACIDSotos syndrome with NSD1 abnormalityuntreatedcontrolRETINOIC ACIDcontroluntreatedcontrolRETINOIC ACIDcontroluntreatedcontrolRETINOIC ACIDcontroluntreatedcontrolRETINOIC ACIDcontroluntreatedcontrolRETINOIC ACIDcontroluntreatedcontrolRETINOIC ACIDcontroluntreatedcontrolRETINOIC ACIDcontroluntreatedcontrolRETINOIC ACIDcontroluntreatedcontrolRETINOIC ACIDcontroluntreated212704Genome-wide expression studies were performed on dermal fibroblasts from Sotos syndrome patients with a confirmed NSD1 abnormality and...E-GEOD-27200/profile/8773/arrayexpressuploader236genomesotos syndromesyndromeDec.12, 2014Falseexpression-data-from-sotos-syndrome-patients-and-cE-GEOD-27200_A-AFFY-44Expression data from Sotos syndrome patients and controlsJul.11, 2014Genome-wide expression studies were performed on dermal fibroblasts from Sotos syndrome patients with a confirmed NSD1 abnormality and compared with age-sex matched controls. We used microarrays to detect differentially expressed genes in Sotos syndrome patients and performed a global test with the aim to map NSD1 within a signaling transduction pathway. Dermal fibroblasts were obtained from nine Sotos syndrome patients and nine controls. Since NSD1 is a co-factor of the retinoic acid receptor, cultures were performed both in the presence and absence of retinoic acid.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-27200http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-27200/samples/